Participation of thromboxane A2 in the cough response in guinea‐pigs: antitussive effect of ozagrel

The purpose of this study was to investigate the involvement of thromboxane A2 (TXA2) in the cough response in a guinea‐pig cough model. Here, we describe results obtained using a selective TXA2 synthetase inhibitor, ozagrel, and a selective TXA2 agonist, U‐46619. Guinea‐pigs were anaesthetized and...

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Veröffentlicht in:	British journal of pharmacology 2000-09, Vol.131 (2), p.266-270
Hauptverfasser:	Shinagawa, Kazuhiko, Kojima, Masami, Ichikawa, Kiyoshi, Hiratochi, Masahiro, Aoyagi, Shigemi, Akahane, Masuo
Format:	Artikel
Sprache:	eng
Schlagworte:	antitussive Biological and medical sciences Cough Medical sciences ozagrel Pharmacology. Drug treatments Respiratory system thromboxane A2 synthetase inhibitor U‐46619
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