In Vitro Assessment of Biodurability: Acellular Systems

In Vitro Assessment of Biodurability: Acellular Systems

The assessment of biodurability of man-made vitreous fibers is essential to the limitation of health hazards associated with human exposure to environments in which respirable fibers are present. In vitro acellular systems provide effective test methods of measuring fiber solubility provided care is...

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Veröffentlicht in:Environmental health perspectives 1994-10, Vol.102 (suppl 5), p.47-53
Hauptverfasser: de Meringo, A., Morscheidt, C., Thélohan, S., Tiesler, H.
Format: Artikel
Sprache:eng
Schlagworte:
Air Pollutants - pharmacokinetics
Animals
Biodegradation, Environmental
Body Fluids - metabolism
Chemical composition
Durability
Extracellular Space - metabolism
Flow velocity
In Vitro Assessment of Biopersistence
Lungs
Materials Testing
Mineral fibers
Physiology
Reproducibility of Results
Solubility
Surface areas
Weight loss
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Beschreibung
Zusammenfassung:The assessment of biodurability of man-made vitreous fibers is essential to the limitation of health hazards associated with human exposure to environments in which respirable fibers are present. In vitro acellular systems provide effective test methods of measuring fiber solubility provided care is taken to select the most suitable solvent and test conditions for the specific fiber type and dimension.
ISSN:0091-6765
1552-9924
DOI:10.1289/ehp.94102s547