Breast feeding conditions a differential developmental pattern of mucosal immunity

A prospective study of 146 children was conducted to evaluate the influence of infant feeding patterns on the development of mucosal immunity. First, there was a trend towards lower IgG concentrations in the breast-fed neonate, indicating a possible earlier 'closure' mechanism of membrane...

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Veröffentlicht in:	Clinical and experimental immunology 1986-10, Vol.66 (1), p.216-222
Hauptverfasser:	GLEESON, M, CRIPPS, A. W, CLANCY, R. L, HENSLEY, M. J, DOBSON, A. J, FIRMAN, D. W
Format:	Artikel
Sprache:	eng
Schlagworte:	Aging Albumins - analysis Biological and medical sciences Breast Feeding Child, Preschool Fundamental and applied biological sciences. Psychology Fundamental immunology General aspects. Ontogeny. Phylogeny Humans Immunobiology Immunoglobulin A, Secretory - analysis Immunoglobulin G - analysis Immunoglobulin M - analysis Immunoglobulins - analysis Infant Infant Nutritional Physiological Phenomena Infant, Newborn Mucous Membrane - immunology Prospective Studies Reference Values Saliva - immunology
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Zusammenfassung:	A prospective study of 146 children was conducted to evaluate the influence of infant feeding patterns on the development of mucosal immunity. First, there was a trend towards lower IgG concentrations in the breast-fed neonate, indicating a possible earlier 'closure' mechanism of membrane permeability. Second, the post-natal increase in IgA was earlier and greater in formula-fed infants. Third, IgM was detected earlier, more frequently, and at higher levels in formula-fed infants.
ISSN:	0009-9104 1365-2249