Assessment of generalisability in trials of health interventions: suggested framework and systematic review

Most evaluations of new treatments use highly selected populations, making it difficult to decide whether they would work elsewhere. Systematic evaluation and reporting of applicability is required

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:BMJ 2006-08, Vol.333 (7563), p.346-349
Hauptverfasser: Bonell, C, Oakley, A, Hargreaves, J, Strange, V, Rees, R
Format: Artikel
Sprache:eng
Schlagworte:
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page 349
container_issue 7563
container_start_page 346
container_title BMJ
container_volume 333
creator Bonell, C
Oakley, A
Hargreaves, J
Strange, V
Rees, R
description Most evaluations of new treatments use highly selected populations, making it difficult to decide whether they would work elsewhere. Systematic evaluation and reporting of applicability is required
doi_str_mv 10.1136/bmj.333.7563.346
format Article
fullrecord <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_1539056</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>57128661</sourcerecordid><originalsourceid>FETCH-LOGICAL-b6616-140fc71fe0cdb14575b036c236bbd8cdf590c3ec0f76d08dc7a5fe76ee470b53</originalsourceid><addsrcrecordid>eNqNkt2L00AUxYMobqn77pMERV809U4m85F9ENbi17IoYvF1mEwm7bT5WGeSrv3vvaFlq8LqPg3M_d3DPYcTRY8JzAih_HXRrGeU0plgnM5oxu9FE5JxmTBJ6f1oAjnLE0moPIlOQ1gDQEqFzDl7GJ0QnkOaEjGJNuch2BAa2_ZxV8VL21qvaxd04WrX72LXxr13ug7jdGV13a_wr7d-ixuua8NZHIbl0obelnHldWOvO7-JdVvGYYefje6dib3dOnv9KHpQoZI9PbzTaPH-3WL-Mbn88uHT_PwyKTgnPCEZVEaQyoIpC5IxwQqg3KSUF0UpTVmxHAy1BirBS5ClEZpVVnBrMwEFo9PozV72aigaWxo8FC2pK-8a7Xeq0079OWndSi27rSKM5oBhTqMXBwHf_RjQmmpcMLaudWu7ISguBRWci_-CTJBUoqc7gCDTPBsVn_0FrrvBt5iWogSAC0A1pJ7eRqWQQSok_acUEULwDHg2hgV7yvguBG-rm5wIqLFmCmumsGZqrJnCmuHKk9_zPS4cSoXA8wOgg9E1tqI1Lhw5CSnkEpBL9pzDovy8mWu_URiuYOrz97m6-Lb4-payCyWRf7nnx5PucOarI320fhv-C0pmBjY</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1777640645</pqid></control><display><type>article</type><title>Assessment of generalisability in trials of health interventions: suggested framework and systematic review</title><source>MEDLINE</source><source>Applied Social Sciences Index &amp; Abstracts (ASSIA)</source><source>BMJ Journals Online Archive</source><source>Alma/SFX Local Collection</source><source>JSTOR</source><creator>Bonell, C ; Oakley, A ; Hargreaves, J ; Strange, V ; Rees, R</creator><creatorcontrib>Bonell, C ; Oakley, A ; Hargreaves, J ; Strange, V ; Rees, R</creatorcontrib><description>Most evaluations of new treatments use highly selected populations, making it difficult to decide whether they would work elsewhere. Systematic evaluation and reporting of applicability is required</description><edition>International edition</edition><identifier>ISSN: 0959-8138</identifier><identifier>ISSN: 0959-8146</identifier><identifier>ISSN: 0959-535X</identifier><identifier>EISSN: 1468-5833</identifier><identifier>EISSN: 1756-1833</identifier><identifier>DOI: 10.1136/bmj.333.7563.346</identifier><identifier>PMID: 16902217</identifier><identifier>CODEN: BMJOAE</identifier><language>eng</language><publisher>London: British Medical Journal Publishing Group</publisher><subject>Analysis and Comment ; Biological and medical sciences ; Clinical trials ; Clinical Trials as Topic - methods ; Clinical Trials as Topic - standards ; Counseling ; Data Interpretation, Statistical ; Disease prevention ; Education ; Effectiveness ; Feasibility ; General aspects ; HIV ; Human immunodeficiency virus ; Humans ; Intervention ; Low income groups ; Medical sciences ; Medical treatment ; Minority &amp; ethnic groups ; Miscellaneous ; Outcome Assessment (Health Care) ; Planning ; Prevention ; Program Evaluation ; Public health. Hygiene ; Public health. Hygiene-occupational medicine ; Randomized controlled trials ; Research methodology ; Sexual health ; Sexually transmitted diseases ; STD ; Systematic review ; Systematic reviews ; Teachers ; Therapeutics - statistics &amp; numerical data ; Treatment Outcome</subject><ispartof>BMJ, 2006-08, Vol.333 (7563), p.346-349</ispartof><rights>2006 BMJ Publishing Group Ltd.</rights><rights>2006 INIST-CNRS</rights><rights>Copyright: 2006 (c) 2006 BMJ Publishing Group Ltd.</rights><rights>Copyright BMJ Publishing Group Aug 12, 2006</rights><rights>2006 2006 BMJ Publishing Group Ltd.</rights><rights>Copyright © 2006, BMJ Publishing Group Ltd. 2006</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-b6616-140fc71fe0cdb14575b036c236bbd8cdf590c3ec0f76d08dc7a5fe76ee470b53</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://bmj.com/content/333/7563/346.full.pdf$$EPDF$$P50$$Gbmj$$H</linktopdf><linktohtml>$$Uhttps://bmj.com/content/333/7563/346.full$$EHTML$$P50$$Gbmj$$H</linktohtml><link.rule.ids>114,115,230,314,780,784,885,3196,23571,27924,27925,30999,31000,55346,77600,77631,77659,77685</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&amp;idt=18020980$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/16902217$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Bonell, C</creatorcontrib><creatorcontrib>Oakley, A</creatorcontrib><creatorcontrib>Hargreaves, J</creatorcontrib><creatorcontrib>Strange, V</creatorcontrib><creatorcontrib>Rees, R</creatorcontrib><title>Assessment of generalisability in trials of health interventions: suggested framework and systematic review</title><title>BMJ</title><addtitle>BMJ</addtitle><addtitle>BMJ</addtitle><description>Most evaluations of new treatments use highly selected populations, making it difficult to decide whether they would work elsewhere. Systematic evaluation and reporting of applicability is required</description><subject>Analysis and Comment</subject><subject>Biological and medical sciences</subject><subject>Clinical trials</subject><subject>Clinical Trials as Topic - methods</subject><subject>Clinical Trials as Topic - standards</subject><subject>Counseling</subject><subject>Data Interpretation, Statistical</subject><subject>Disease prevention</subject><subject>Education</subject><subject>Effectiveness</subject><subject>Feasibility</subject><subject>General aspects</subject><subject>HIV</subject><subject>Human immunodeficiency virus</subject><subject>Humans</subject><subject>Intervention</subject><subject>Low income groups</subject><subject>Medical sciences</subject><subject>Medical treatment</subject><subject>Minority &amp; ethnic groups</subject><subject>Miscellaneous</subject><subject>Outcome Assessment (Health Care)</subject><subject>Planning</subject><subject>Prevention</subject><subject>Program Evaluation</subject><subject>Public health. Hygiene</subject><subject>Public health. Hygiene-occupational medicine</subject><subject>Randomized controlled trials</subject><subject>Research methodology</subject><subject>Sexual health</subject><subject>Sexually transmitted diseases</subject><subject>STD</subject><subject>Systematic review</subject><subject>Systematic reviews</subject><subject>Teachers</subject><subject>Therapeutics - statistics &amp; numerical data</subject><subject>Treatment Outcome</subject><issn>0959-8138</issn><issn>0959-8146</issn><issn>0959-535X</issn><issn>1468-5833</issn><issn>1756-1833</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2006</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>8G5</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><sourceid>GUQSH</sourceid><sourceid>M2O</sourceid><sourceid>7QJ</sourceid><recordid>eNqNkt2L00AUxYMobqn77pMERV809U4m85F9ENbi17IoYvF1mEwm7bT5WGeSrv3vvaFlq8LqPg3M_d3DPYcTRY8JzAih_HXRrGeU0plgnM5oxu9FE5JxmTBJ6f1oAjnLE0moPIlOQ1gDQEqFzDl7GJ0QnkOaEjGJNuch2BAa2_ZxV8VL21qvaxd04WrX72LXxr13ug7jdGV13a_wr7d-ixuua8NZHIbl0obelnHldWOvO7-JdVvGYYefje6dib3dOnv9KHpQoZI9PbzTaPH-3WL-Mbn88uHT_PwyKTgnPCEZVEaQyoIpC5IxwQqg3KSUF0UpTVmxHAy1BirBS5ClEZpVVnBrMwEFo9PozV72aigaWxo8FC2pK-8a7Xeq0079OWndSi27rSKM5oBhTqMXBwHf_RjQmmpcMLaudWu7ISguBRWci_-CTJBUoqc7gCDTPBsVn_0FrrvBt5iWogSAC0A1pJ7eRqWQQSok_acUEULwDHg2hgV7yvguBG-rm5wIqLFmCmumsGZqrJnCmuHKk9_zPS4cSoXA8wOgg9E1tqI1Lhw5CSnkEpBL9pzDovy8mWu_URiuYOrz97m6-Lb4-payCyWRf7nnx5PucOarI320fhv-C0pmBjY</recordid><startdate>20060812</startdate><enddate>20060812</enddate><creator>Bonell, C</creator><creator>Oakley, A</creator><creator>Hargreaves, J</creator><creator>Strange, V</creator><creator>Rees, R</creator><general>British Medical Journal Publishing Group</general><general>British Medical Association</general><general>BMJ Publishing Group LTD</general><general>BMJ Publishing Group</general><general>BMJ Publishing Group Ltd</general><scope>BSCLL</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>88I</scope><scope>8AF</scope><scope>8FE</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>8G5</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>ASE</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>BTHHO</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FPQ</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>GUQSH</scope><scope>HCIFZ</scope><scope>K6X</scope><scope>K9.</scope><scope>LK8</scope><scope>M2O</scope><scope>M2P</scope><scope>M7P</scope><scope>MBDVC</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>Q9U</scope><scope>7QJ</scope><scope>7RV</scope><scope>KB0</scope><scope>NAPCQ</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20060812</creationdate><title>Assessment of generalisability in trials of health interventions: suggested framework and systematic review</title><author>Bonell, C ; Oakley, A ; Hargreaves, J ; Strange, V ; Rees, R</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-b6616-140fc71fe0cdb14575b036c236bbd8cdf590c3ec0f76d08dc7a5fe76ee470b53</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2006</creationdate><topic>Analysis and Comment</topic><topic>Biological and medical sciences</topic><topic>Clinical trials</topic><topic>Clinical Trials as Topic - methods</topic><topic>Clinical Trials as Topic - standards</topic><topic>Counseling</topic><topic>Data Interpretation, Statistical</topic><topic>Disease prevention</topic><topic>Education</topic><topic>Effectiveness</topic><topic>Feasibility</topic><topic>General aspects</topic><topic>HIV</topic><topic>Human immunodeficiency virus</topic><topic>Humans</topic><topic>Intervention</topic><topic>Low income groups</topic><topic>Medical sciences</topic><topic>Medical treatment</topic><topic>Minority &amp; ethnic groups</topic><topic>Miscellaneous</topic><topic>Outcome Assessment (Health Care)</topic><topic>Planning</topic><topic>Prevention</topic><topic>Program Evaluation</topic><topic>Public health. Hygiene</topic><topic>Public health. Hygiene-occupational medicine</topic><topic>Randomized controlled trials</topic><topic>Research methodology</topic><topic>Sexual health</topic><topic>Sexually transmitted diseases</topic><topic>STD</topic><topic>Systematic review</topic><topic>Systematic reviews</topic><topic>Teachers</topic><topic>Therapeutics - statistics &amp; numerical data</topic><topic>Treatment Outcome</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Bonell, C</creatorcontrib><creatorcontrib>Oakley, A</creatorcontrib><creatorcontrib>Hargreaves, J</creatorcontrib><creatorcontrib>Strange, V</creatorcontrib><creatorcontrib>Rees, R</creatorcontrib><collection>Istex</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>PHMC-Proquest健康医学期刊库</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Science Database (Alumni Edition)</collection><collection>STEM Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Research Library (Alumni Edition)</collection><collection>ProQuest Central (Alumni)</collection><collection>ProQuest Central</collection><collection>British Nursing Index</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>AUTh Library subscriptions: ProQuest Central</collection><collection>ProQuest Natural Science Collection</collection><collection>BMJ Journals</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central</collection><collection>British Nursing Index (BNI) (1985 to Present)</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>Research Library Prep</collection><collection>SciTech Premium Collection</collection><collection>British Nursing Index</collection><collection>ProQuest Health &amp; Medical Complete (Alumni)</collection><collection>ProQuest Biological Science Collection</collection><collection>ProQuest research library</collection><collection>ProQuest Science Journals</collection><collection>ProQuest Biological Science Journals</collection><collection>Research Library (Corporate)</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>ProQuest Central Basic</collection><collection>Applied Social Sciences Index &amp; Abstracts (ASSIA)</collection><collection>Nursing &amp; Allied Health Database</collection><collection>Nursing &amp; Allied Health Database (Alumni Edition)</collection><collection>Nursing &amp; Allied Health Premium</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>BMJ</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Bonell, C</au><au>Oakley, A</au><au>Hargreaves, J</au><au>Strange, V</au><au>Rees, R</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Assessment of generalisability in trials of health interventions: suggested framework and systematic review</atitle><jtitle>BMJ</jtitle><stitle>BMJ</stitle><addtitle>BMJ</addtitle><date>2006-08-12</date><risdate>2006</risdate><volume>333</volume><issue>7563</issue><spage>346</spage><epage>349</epage><pages>346-349</pages><issn>0959-8138</issn><issn>0959-8146</issn><issn>0959-535X</issn><eissn>1468-5833</eissn><eissn>1756-1833</eissn><coden>BMJOAE</coden><abstract>Most evaluations of new treatments use highly selected populations, making it difficult to decide whether they would work elsewhere. Systematic evaluation and reporting of applicability is required</abstract><cop>London</cop><pub>British Medical Journal Publishing Group</pub><pmid>16902217</pmid><doi>10.1136/bmj.333.7563.346</doi><tpages>4</tpages><edition>International edition</edition><oa>free_for_read</oa></addata></record>
fulltext fulltext
identifier ISSN: 0959-8138
ispartof BMJ, 2006-08, Vol.333 (7563), p.346-349
issn 0959-8138
0959-8146
0959-535X
1468-5833
1756-1833
language eng
recordid cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_1539056
source MEDLINE; Applied Social Sciences Index & Abstracts (ASSIA); BMJ Journals Online Archive; Alma/SFX Local Collection; JSTOR
subjects Analysis and Comment
Biological and medical sciences
Clinical trials
Clinical Trials as Topic - methods
Clinical Trials as Topic - standards
Counseling
Data Interpretation, Statistical
Disease prevention
Education
Effectiveness
Feasibility
General aspects
HIV
Human immunodeficiency virus
Humans
Intervention
Low income groups
Medical sciences
Medical treatment
Minority & ethnic groups
Miscellaneous
Outcome Assessment (Health Care)
Planning
Prevention
Program Evaluation
Public health. Hygiene
Public health. Hygiene-occupational medicine
Randomized controlled trials
Research methodology
Sexual health
Sexually transmitted diseases
STD
Systematic review
Systematic reviews
Teachers
Therapeutics - statistics & numerical data
Treatment Outcome
title Assessment of generalisability in trials of health interventions: suggested framework and systematic review
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-25T11%3A07%3A04IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Assessment%20of%20generalisability%20in%20trials%20of%20health%20interventions:%20suggested%20framework%20and%20systematic%20review&rft.jtitle=BMJ&rft.au=Bonell,%20C&rft.date=2006-08-12&rft.volume=333&rft.issue=7563&rft.spage=346&rft.epage=349&rft.pages=346-349&rft.issn=0959-8138&rft.eissn=1468-5833&rft.coden=BMJOAE&rft_id=info:doi/10.1136/bmj.333.7563.346&rft_dat=%3Cproquest_pubme%3E57128661%3C/proquest_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1777640645&rft_id=info:pmid/16902217&rfr_iscdi=true