T cell subset alterations in idiopathic glomerulonephritis
Peripheral blood lymphocytes from 15 healthy controls and 59 patients with idiopathic glomerulonephritis were studied to determine whether an imbalance exists among human T cell subsets in these diseases. The data shows that the functional lymphocyte disorders previously described in minimal change...
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Veröffentlicht in: | Clinical and experimental immunology 1982-10, Vol.50 (1), p.70-76 |
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creator | Cagnoli, L Tabacchi, P Pasquali, S Cenci, M Sasdelli, M Zucchelli, P |
description | Peripheral blood lymphocytes from 15 healthy controls and 59 patients with idiopathic glomerulonephritis were studied to determine whether an imbalance exists among human T cell subsets in these diseases. The data shows that the functional lymphocyte disorders previously described in minimal change nephropathy and IgA glomerulonephritis are not due to a numerical imbalance of lymphocyte subsets. Such an imbalance of lymphocyte subsets was specifically observed in membranous glomerulonephritis with nephrotic syndrome. The true significance of this finding has to be clarified by longitudinal studies and functional tests. |
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The data shows that the functional lymphocyte disorders previously described in minimal change nephropathy and IgA glomerulonephritis are not due to a numerical imbalance of lymphocyte subsets. Such an imbalance of lymphocyte subsets was specifically observed in membranous glomerulonephritis with nephrotic syndrome. 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The data shows that the functional lymphocyte disorders previously described in minimal change nephropathy and IgA glomerulonephritis are not due to a numerical imbalance of lymphocyte subsets. Such an imbalance of lymphocyte subsets was specifically observed in membranous glomerulonephritis with nephrotic syndrome. The true significance of this finding has to be clarified by longitudinal studies and functional tests.</description><subject>Adolescent</subject><subject>Adult</subject><subject>Aged</subject><subject>Child</subject><subject>Glomerulonephritis - immunology</subject><subject>Humans</subject><subject>Leukocyte Count</subject><subject>Middle Aged</subject><subject>Nephrosis, Lipoid - immunology</subject><subject>T-Lymphocytes - classification</subject><subject>T-Lymphocytes - immunology</subject><subject>T-Lymphocytes, Helper-Inducer - immunology</subject><subject>T-Lymphocytes, Regulatory - immunology</subject><issn>0009-9104</issn><issn>1365-2249</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1982</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkE1LxDAQhoMo67r6E4SevBUmk49uPAiy-AULXtZzSNvsbiRtapIK_nsrLqInT8MwDw_vvEdkTpkUJSJXx2QOAKpUFPgpOUvpdVqllDgjM4m0AmBzcr0pGut9kcY62VwYn2002YU-Fa4vXOvCYPLeNcXOh87G0YfeDvvoskvn5GRrfLIXh7kgL_d3m9VjuX5-eFrdrssBFeZSIKCoW1TKUlE1RmIjlsAt3ZqWoWQAWAnWIMcpHlAqWgoGKCjOW8omZkFuvr3DWHe2bWyfo_F6iK4z8UMH4_TfS-_2ehfeNRVMLjmbBFcHQQxvo01Zdy59fW16G8akl4BUAId_QcqE5JJXE3j5O9JPlkOt7BM_H3Qq</recordid><startdate>19821001</startdate><enddate>19821001</enddate><creator>Cagnoli, L</creator><creator>Tabacchi, P</creator><creator>Pasquali, S</creator><creator>Cenci, M</creator><creator>Sasdelli, M</creator><creator>Zucchelli, P</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7T5</scope><scope>H94</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>19821001</creationdate><title>T cell subset alterations in idiopathic glomerulonephritis</title><author>Cagnoli, L ; Tabacchi, P ; Pasquali, S ; Cenci, M ; Sasdelli, M ; Zucchelli, P</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-p292t-52025bd299e157ca62c5804e1fad3263002753c2420000115d10a010944d13ad3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1982</creationdate><topic>Adolescent</topic><topic>Adult</topic><topic>Aged</topic><topic>Child</topic><topic>Glomerulonephritis - immunology</topic><topic>Humans</topic><topic>Leukocyte Count</topic><topic>Middle Aged</topic><topic>Nephrosis, Lipoid - immunology</topic><topic>T-Lymphocytes - classification</topic><topic>T-Lymphocytes - immunology</topic><topic>T-Lymphocytes, Helper-Inducer - immunology</topic><topic>T-Lymphocytes, Regulatory - immunology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Cagnoli, L</creatorcontrib><creatorcontrib>Tabacchi, P</creatorcontrib><creatorcontrib>Pasquali, S</creatorcontrib><creatorcontrib>Cenci, M</creatorcontrib><creatorcontrib>Sasdelli, M</creatorcontrib><creatorcontrib>Zucchelli, P</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>Immunology Abstracts</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Clinical and experimental immunology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Cagnoli, L</au><au>Tabacchi, P</au><au>Pasquali, S</au><au>Cenci, M</au><au>Sasdelli, M</au><au>Zucchelli, P</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>T cell subset alterations in idiopathic glomerulonephritis</atitle><jtitle>Clinical and experimental immunology</jtitle><addtitle>Clin Exp Immunol</addtitle><date>1982-10-01</date><risdate>1982</risdate><volume>50</volume><issue>1</issue><spage>70</spage><epage>76</epage><pages>70-76</pages><issn>0009-9104</issn><eissn>1365-2249</eissn><abstract>Peripheral blood lymphocytes from 15 healthy controls and 59 patients with idiopathic glomerulonephritis were studied to determine whether an imbalance exists among human T cell subsets in these diseases. The data shows that the functional lymphocyte disorders previously described in minimal change nephropathy and IgA glomerulonephritis are not due to a numerical imbalance of lymphocyte subsets. Such an imbalance of lymphocyte subsets was specifically observed in membranous glomerulonephritis with nephrotic syndrome. The true significance of this finding has to be clarified by longitudinal studies and functional tests.</abstract><cop>England</cop><pmid>6217003</pmid><tpages>7</tpages></addata></record> |
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subjects | Adolescent Adult Aged Child Glomerulonephritis - immunology Humans Leukocyte Count Middle Aged Nephrosis, Lipoid - immunology T-Lymphocytes - classification T-Lymphocytes - immunology T-Lymphocytes, Helper-Inducer - immunology T-Lymphocytes, Regulatory - immunology |
title | T cell subset alterations in idiopathic glomerulonephritis |
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