T cell subset alterations in idiopathic glomerulonephritis
Peripheral blood lymphocytes from 15 healthy controls and 59 patients with idiopathic glomerulonephritis were studied to determine whether an imbalance exists among human T cell subsets in these diseases. The data shows that the functional lymphocyte disorders previously described in minimal change...
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Veröffentlicht in: | Clinical and experimental immunology 1982-10, Vol.50 (1), p.70-76 |
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Format: | Artikel |
Sprache: | eng |
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Zusammenfassung: | Peripheral blood lymphocytes from 15 healthy controls and 59 patients with idiopathic glomerulonephritis were studied to determine whether an imbalance exists among human T cell subsets in these diseases. The data shows that the functional lymphocyte disorders previously described in minimal change nephropathy and IgA glomerulonephritis are not due to a numerical imbalance of lymphocyte subsets. Such an imbalance of lymphocyte subsets was specifically observed in membranous glomerulonephritis with nephrotic syndrome. The true significance of this finding has to be clarified by longitudinal studies and functional tests. |
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ISSN: | 0009-9104 1365-2249 |