EFFECT OF RESERPINE ON GROWTH AND SEXUAL DEVELOPMENT OF CHICKENS

EFFECT OF RESERPINE ON GROWTH AND SEXUAL DEVELOPMENT OF CHICKENS

One‐month‐old male chickens were given injections of 1 mg, 2 mg and 4 mg/kg of reserpine. The injections were repeated at weekly intervals for three months. The chickens receiving reserpine grew at half the rate of untreated control chickens and failed to grow combs. At 4 months of age the testes of...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:British Journal of Pharmacology and Chemotherapy 1961-10, Vol.17 (2), p.267-275
Hauptverfasser: HAGEN, P., WALLACE, A. C.
Format: Artikel
Sprache:eng
Schlagworte:
Animals
Atrophy
Body Weight
Chickens
Comb and Wattles
Growth - pharmacology
Humans
Male
Old Medline
Reserpine - pharmacology
Seminiferous Tubules
Sexual Development
Testis - pharmacology
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:One‐month‐old male chickens were given injections of 1 mg, 2 mg and 4 mg/kg of reserpine. The injections were repeated at weekly intervals for three months. The chickens receiving reserpine grew at half the rate of untreated control chickens and failed to grow combs. At 4 months of age the testes of reserpine‐treated chickens were only about one‐tenth the weight of the testes of the control chickens and histologically they showed extreme hypoplasia of the seminiferous tubules. Two large doses of reserpine one month apart could cause atrophy of the testes of adult roosters.
ISSN:0366-0826
1476-5381
DOI:10.1111/j.1476-5381.1961.tb01287.x