Clinical observations of the treatment of canine perianal fistulas with topical tacrolimus in 10 dogs

Tacrolimus ointment, a potent immunosuppressive medication, was evaluated for efficacy in the treatment of perianal fistulas in dogs. Ten dogs with perianal fistulas were treated with topical tacrolimus ointment once to twice daily for 16 weeks. Full healing of the fistulas occurred in 50% and was n...

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Veröffentlicht in:	Canadian veterinary journal 2000-08, Vol.41 (8), p.623-627
Hauptverfasser:	Misseghers, B S, Binnington, A G, Mathews, K A
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Topical Animals Dog Diseases - drug therapy Dog Diseases - pathology Dogs Female Immunosuppressive Agents - administration & dosage Immunosuppressive Agents - pharmacology Immunosuppressive Agents - therapeutic use Male Rectal Fistula - drug therapy Rectal Fistula - veterinary Tacrolimus - administration & dosage Tacrolimus - pharmacology Tacrolimus - therapeutic use Treatment Outcome
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Zusammenfassung:	Tacrolimus ointment, a potent immunosuppressive medication, was evaluated for efficacy in the treatment of perianal fistulas in dogs. Ten dogs with perianal fistulas were treated with topical tacrolimus ointment once to twice daily for 16 weeks. Full healing of the fistulas occurred in 50% and was noticeably improved in 90% of dogs.
ISSN:	0008-5286