Functional role of TRPC proteins in native systems: implications from knockout and knock-down studies

Available data on transient receptor potential channel (TRPC) protein functions indicate that these proteins represent essential constituents of agonist-activated and phospholipase C-dependent cation entry pathways in primary cells which contribute to the elevation of cytosolic Ca 2+ . In addition,...

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Veröffentlicht in:	The Journal of physiology 2005-08, Vol.567 (1), p.59-66
Hauptverfasser:	Freichel, Marc, Vennekens, Rudi, Olausson, Jenny, Stolz, Susanne, Philipp, Stephan E., Weißgerber, Petra, Flockerzi, Veit
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Calcium Channels - genetics Calcium Channels - physiology Gene Silencing Humans Ion Channels - genetics Ion Channels - physiology Mice Mice, Knockout TRP Channels TRPC Cation Channels
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