Carcinogenicity Predictions for a Group of 30 Chemicals Undergoing Rodent Cancer Bioassays Based on Rules Derived from Subchronic Organ Toxicities

Rodent carcinogenicities for a group of 30 chemicals which form the subject of the Second NIEHS Predictive-Toxicology Evaluation Experiment are predicted based on their subchronic organ toxicities. Predictions are made by rules learned by the rule learning (RL) induction program.

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Bibliographische Detailangaben
Veröffentlicht in:	Environmental Health Perspectives 1996-10, Vol.104 (suppl 5), p.1059-1063
Hauptverfasser:	Lee, Yongwon, Buchanan, Bruce G., Rosenkranz, Herbert S.
Format:	Artikel
Sprache:	eng
Schlagworte:	02 PETROLEUM Animals BIOLOGICAL EFFECTS BIOLOGY AND MEDICINE, APPLIED STUDIES CALCULATION METHODS Carcinogenicity Carcinogenicity Tests CARCINOGENS Carcinogens - toxicity Chemical hazards FORECASTING Hyperplasia Inflammation Kidneys Lesions Liver MATHEMATICS, COMPUTERS, INFORMATION SCIENCE, MANAGEMENT, LAW, MISCELLANEOUS Mice NEOPLASMS OCCUPATIONAL EXPOSURE Organ Specificity ORGANIC COMPOUNDS PETROCHEMICALS PETROLEUM INDUSTRY PROBABILITY Rats RODENTS Spleen STRUCTURE-ACTIVITY RELATIONSHIPS The Second NIEHS Predictive-Toxicology Evaluation Experiment: 30 Chemical Carcinogenicity Bioassays
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Beschreibung
Zusammenfassung:	Rodent carcinogenicities for a group of 30 chemicals which form the subject of the Second NIEHS Predictive-Toxicology Evaluation Experiment are predicted based on their subchronic organ toxicities. Predictions are made by rules learned by the rule learning (RL) induction program.
ISSN:	0091-6765 1552-9924
DOI:	10.1289/ehp.96104s51059