Effect of aspirin on nasal resistance to airflow

The effect of aspirin on nasal resistance to airflow was investigated by rhinomanometry in 25 healthy subjects before and after ingestion of aspirin or vitamin C in a double blind crossover trial. Aspirin caused a significant increase in nasal resistance compared with vitamin C. The effect of aspiri...

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Veröffentlicht in:	BMJ 1985-04, Vol.290 (6476), p.1171-1173
Hauptverfasser:	Jones, A S, Lancer, J M, Moir, A A, Stevens, J C
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Airway Resistance - drug effects Aspirin - pharmacology Double-Blind Method Female Humans Ingestion Male Nasal Cavity - drug effects Nasal mucosa Nasal obstruction Otolaryngology Placebos Prostaglandins T tests Vitamin C
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Beschreibung
Zusammenfassung:	The effect of aspirin on nasal resistance to airflow was investigated by rhinomanometry in 25 healthy subjects before and after ingestion of aspirin or vitamin C in a double blind crossover trial. Aspirin caused a significant increase in nasal resistance compared with vitamin C. The effect of aspirin may be due to its inhibition of the synthesis of prostaglandins.
ISSN:	0267-0623 0959-8138 1468-5833
DOI:	10.1136/bmj.290.6476.1171