A comparison of the amounts and the antigenicity of polymeric materials formed in aqueous solution by some beta-lactam antibiotics
Concentrated aqueous solutions of some β-lactam antibiotics were stored for 14 days. Samples were then subjected to gel filtration and fractions in the high molecular weight regions of the eluate were collected and lyophilized. The yields of materials from solutions of various β-lactam antibiotics w...
Gespeichert in:
| Veröffentlicht in: | Immunology 1971-09, Vol.21 (3), p.527-533 |
|---|---|
| Hauptverfasser: | , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 533 |
|---|---|
| container_issue | 3 |
| container_start_page | 527 |
| container_title | Immunology |
| container_volume | 21 |
| creator | Smith, H Dewdney, J M Wheeler, A W |
| description | Concentrated aqueous solutions of some β-lactam antibiotics were stored for 14 days. Samples were then subjected to gel filtration and fractions in the high molecular weight regions of the eluate were collected and lyophilized. The yields of materials from solutions of various β-lactam antibiotics were compared and the antigenicity of the materials was assessed by their ability to react with antibodies of benzylpenicilloyl specificity raised in rabbits and tested in guinea-pigs by passive cutaneous anaphylaxis. |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_1408159</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>73536114</sourcerecordid><originalsourceid>FETCH-LOGICAL-p261t-8fb905f16370c5d7a0cf4a4309502ff0601b59d4d42e286be0480d797f4b797b3</originalsourceid><addsrcrecordid>eNpVkMtKxDAUhoMo4zj6CEJW7gpJc2m7EYbBGwhudF2SNJmJNEltUqFbn9yMM4huzoXz8_3nnBOwxISzomS8OgVLhHBTlDVi5-AixvfcEsTYAiwY4zUp6yX4WkMV3CBGG4OHwcC001C4MPkUofDdoffJbrW3yqZ5rxlCPzs9WgWdSDmLPkITRqc7aD0UH5MOU4Qx9FOymSrnXDsNpU6i6IVKwv0gpQ3JqngJzkwm6KtjXoG3-7vXzWPx_PLwtFk_F0PJcSpqIxvEDOakQop1lUDKUEEJahgqjUEcYcmajna01GXNpUa0Rl3VVIbKHCVZgdsDd5hkXlVpn0bRt8NonRjnNgjb_p94u2u34bPFFNWYNRlwcwSMId8YU-tsVLrvhd8f3FaEEY4xzcLrv06_Fsevk28BGILl</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>73536114</pqid></control><display><type>article</type><title>A comparison of the amounts and the antigenicity of polymeric materials formed in aqueous solution by some beta-lactam antibiotics</title><source>MEDLINE</source><source>EZB-FREE-00999 freely available EZB journals</source><source>PubMed Central</source><creator>Smith, H ; Dewdney, J M ; Wheeler, A W</creator><creatorcontrib>Smith, H ; Dewdney, J M ; Wheeler, A W</creatorcontrib><description>Concentrated aqueous solutions of some β-lactam antibiotics were stored for 14 days. Samples were then subjected to gel filtration and fractions in the high molecular weight regions of the eluate were collected and lyophilized. The yields of materials from solutions of various β-lactam antibiotics were compared and the antigenicity of the materials was assessed by their ability to react with antibodies of benzylpenicilloyl specificity raised in rabbits and tested in guinea-pigs by passive cutaneous anaphylaxis.</description><identifier>ISSN: 0019-2805</identifier><identifier>EISSN: 1365-2567</identifier><identifier>PMID: 5568328</identifier><language>eng</language><publisher>England</publisher><subject>Ampicillin ; Animals ; Antibodies ; Carbenicillin ; Chromatography, Gel ; Guinea Pigs ; Immune Sera ; Molecular Weight ; Passive Cutaneous Anaphylaxis ; Penicillin G ; Penicillins ; Polymers ; Rabbits ; Solutions ; Water</subject><ispartof>Immunology, 1971-09, Vol.21 (3), p.527-533</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC1408159/pdf/$$EPDF$$P50$$Gpubmedcentral$$H</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC1408159/$$EHTML$$P50$$Gpubmedcentral$$H</linktohtml><link.rule.ids>230,314,727,780,784,885,53789,53791</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/5568328$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Smith, H</creatorcontrib><creatorcontrib>Dewdney, J M</creatorcontrib><creatorcontrib>Wheeler, A W</creatorcontrib><title>A comparison of the amounts and the antigenicity of polymeric materials formed in aqueous solution by some beta-lactam antibiotics</title><title>Immunology</title><addtitle>Immunology</addtitle><description>Concentrated aqueous solutions of some β-lactam antibiotics were stored for 14 days. Samples were then subjected to gel filtration and fractions in the high molecular weight regions of the eluate were collected and lyophilized. The yields of materials from solutions of various β-lactam antibiotics were compared and the antigenicity of the materials was assessed by their ability to react with antibodies of benzylpenicilloyl specificity raised in rabbits and tested in guinea-pigs by passive cutaneous anaphylaxis.</description><subject>Ampicillin</subject><subject>Animals</subject><subject>Antibodies</subject><subject>Carbenicillin</subject><subject>Chromatography, Gel</subject><subject>Guinea Pigs</subject><subject>Immune Sera</subject><subject>Molecular Weight</subject><subject>Passive Cutaneous Anaphylaxis</subject><subject>Penicillin G</subject><subject>Penicillins</subject><subject>Polymers</subject><subject>Rabbits</subject><subject>Solutions</subject><subject>Water</subject><issn>0019-2805</issn><issn>1365-2567</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1971</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpVkMtKxDAUhoMo4zj6CEJW7gpJc2m7EYbBGwhudF2SNJmJNEltUqFbn9yMM4huzoXz8_3nnBOwxISzomS8OgVLhHBTlDVi5-AixvfcEsTYAiwY4zUp6yX4WkMV3CBGG4OHwcC001C4MPkUofDdoffJbrW3yqZ5rxlCPzs9WgWdSDmLPkITRqc7aD0UH5MOU4Qx9FOymSrnXDsNpU6i6IVKwv0gpQ3JqngJzkwm6KtjXoG3-7vXzWPx_PLwtFk_F0PJcSpqIxvEDOakQop1lUDKUEEJahgqjUEcYcmajna01GXNpUa0Rl3VVIbKHCVZgdsDd5hkXlVpn0bRt8NonRjnNgjb_p94u2u34bPFFNWYNRlwcwSMId8YU-tsVLrvhd8f3FaEEY4xzcLrv06_Fsevk28BGILl</recordid><startdate>197109</startdate><enddate>197109</enddate><creator>Smith, H</creator><creator>Dewdney, J M</creator><creator>Wheeler, A W</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>197109</creationdate><title>A comparison of the amounts and the antigenicity of polymeric materials formed in aqueous solution by some beta-lactam antibiotics</title><author>Smith, H ; Dewdney, J M ; Wheeler, A W</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-p261t-8fb905f16370c5d7a0cf4a4309502ff0601b59d4d42e286be0480d797f4b797b3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1971</creationdate><topic>Ampicillin</topic><topic>Animals</topic><topic>Antibodies</topic><topic>Carbenicillin</topic><topic>Chromatography, Gel</topic><topic>Guinea Pigs</topic><topic>Immune Sera</topic><topic>Molecular Weight</topic><topic>Passive Cutaneous Anaphylaxis</topic><topic>Penicillin G</topic><topic>Penicillins</topic><topic>Polymers</topic><topic>Rabbits</topic><topic>Solutions</topic><topic>Water</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Smith, H</creatorcontrib><creatorcontrib>Dewdney, J M</creatorcontrib><creatorcontrib>Wheeler, A W</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Immunology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Smith, H</au><au>Dewdney, J M</au><au>Wheeler, A W</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>A comparison of the amounts and the antigenicity of polymeric materials formed in aqueous solution by some beta-lactam antibiotics</atitle><jtitle>Immunology</jtitle><addtitle>Immunology</addtitle><date>1971-09</date><risdate>1971</risdate><volume>21</volume><issue>3</issue><spage>527</spage><epage>533</epage><pages>527-533</pages><issn>0019-2805</issn><eissn>1365-2567</eissn><abstract>Concentrated aqueous solutions of some β-lactam antibiotics were stored for 14 days. Samples were then subjected to gel filtration and fractions in the high molecular weight regions of the eluate were collected and lyophilized. The yields of materials from solutions of various β-lactam antibiotics were compared and the antigenicity of the materials was assessed by their ability to react with antibodies of benzylpenicilloyl specificity raised in rabbits and tested in guinea-pigs by passive cutaneous anaphylaxis.</abstract><cop>England</cop><pmid>5568328</pmid><tpages>7</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0019-2805 |
| ispartof | Immunology, 1971-09, Vol.21 (3), p.527-533 |
| issn | 0019-2805 1365-2567 |
| language | eng |
| recordid | cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_1408159 |
| source | MEDLINE; EZB-FREE-00999 freely available EZB journals; PubMed Central |
| subjects | Ampicillin Animals Antibodies Carbenicillin Chromatography, Gel Guinea Pigs Immune Sera Molecular Weight Passive Cutaneous Anaphylaxis Penicillin G Penicillins Polymers Rabbits Solutions Water |
| title | A comparison of the amounts and the antigenicity of polymeric materials formed in aqueous solution by some beta-lactam antibiotics |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-10T00%3A22%3A06IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=A%20comparison%20of%20the%20amounts%20and%20the%20antigenicity%20of%20polymeric%20materials%20formed%20in%20aqueous%20solution%20by%20some%20beta-lactam%20antibiotics&rft.jtitle=Immunology&rft.au=Smith,%20H&rft.date=1971-09&rft.volume=21&rft.issue=3&rft.spage=527&rft.epage=533&rft.pages=527-533&rft.issn=0019-2805&rft.eissn=1365-2567&rft_id=info:doi/&rft_dat=%3Cproquest_pubme%3E73536114%3C/proquest_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=73536114&rft_id=info:pmid/5568328&rfr_iscdi=true |