Interaction between flurbiprofen and indomethacin in rheumatoid arthritis
The aim of this study was to measure serum levels of flurbiprofen and indomethacin when administered alone or in combination. Changes in clinical effect and toxicity were also noted. Ten patients with classical or definite rheumatoid arthritis (RA) according to the American Rheumatism Association...
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Veröffentlicht in: | British journal of clinical pharmacology 1982-03, Vol.13 (3), p.448-451 |
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container_title | British journal of clinical pharmacology |
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creator | Rudge, SR Lloyd‐Jones, JK Hind, ID |
description | The aim of this study was to measure serum levels of flurbiprofen and indomethacin when administered alone or in combination. Changes in clinical effect and toxicity were also noted. Ten patients with classical or definite rheumatoid arthritis (RA) according to the American Rheumatism Association's criteria agreed to take part in the study, which was approved by the Hospital Ethical Committee. All were female with ages ranging from 29-64 years (median 55 years) and a disease duration from 6 months-22 years (median 5 years). |
doi_str_mv | 10.1111/j.1365-2125.1982.tb01401.x |
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Changes in clinical effect and toxicity were also noted. Ten patients with classical or definite rheumatoid arthritis (RA) according to the American Rheumatism Association's criteria agreed to take part in the study, which was approved by the Hospital Ethical Committee. 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source | MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; Alma/SFX Local Collection |
subjects | Adolescent Adult Arthritis, Rheumatoid - drug therapy Child Child, Preschool Clinical Trials as Topic Double-Blind Method Drug Interactions Female Flurbiprofen - blood Flurbiprofen - therapeutic use Humans Indomethacin - blood Indomethacin - therapeutic use Infant Propionates - therapeutic use |
title | Interaction between flurbiprofen and indomethacin in rheumatoid arthritis |
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