The effect of co‐trimoxazole on serum creatinine

The effect of co‐trimoxazole on serum creatinine

1 Co‐trimoxazole induces a highly significant and reversible elevation of the serum creatinine level. 2 In renal‐allograft patients the degree of this elevation is significantly correlated with the concentration of serum creatinine before administration of co‐trimoxazole and with the concentration o...

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Veröffentlicht in:British journal of clinical pharmacology 1981-11, Vol.12 (5), p.701-703
Hauptverfasser: Dijkmans, BA, Hooff, JP, Wolff, FA, Mattie, H
Format: Artikel
Sprache:eng
Schlagworte:
Anti-Infective Agents - pharmacology
Creatinine - blood
Drug Combinations - pharmacology
Female
Humans
Male
Sulfamethoxazole - pharmacology
Trimethoprim - pharmacology
Trimethoprim, Sulfamethoxazole Drug Combination
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Beschreibung
Zusammenfassung:1 Co‐trimoxazole induces a highly significant and reversible elevation of the serum creatinine level. 2 In renal‐allograft patients the degree of this elevation is significantly correlated with the concentration of serum creatinine before administration of co‐trimoxazole and with the concentration of non‐protein‐bound trimethoprim.
ISSN:0306-5251
1365-2125
DOI:10.1111/j.1365-2125.1981.tb01293.x