Does melatonin improve sleep?: Muddles with melatonin

Does melatonin improve sleep?: Muddles with melatonin

Too low a dose and no effect, too high and the chronobiological effects are lost and only the direct somnolent action is experienced. [...]very recently there have been no commercially available preparations of the correct dose, substantially hindering research.

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Bibliographische Detailangaben
Veröffentlicht in:BMJ 2006-03, Vol.332 (7540), p.550-550
1. Verfasser: Wise, M E Jan
Format: Artikel
Sprache:eng
Schlagworte:
Circadian rhythm
Circadian Rhythm - drug effects
Humans
Letters
Melatonin - administration & dosage
Sleep disorders
Sleep Wake Disorders - drug therapy
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Beschreibung
Zusammenfassung:Too low a dose and no effect, too high and the chronobiological effects are lost and only the direct somnolent action is experienced. [...]very recently there have been no commercially available preparations of the correct dose, substantially hindering research.
ISSN:0959-8138
1468-5833
1756-1833
DOI:10.1136/bmj.332.7540.550-a