Absence of a pharmacokinetic interaction between enalapril and frusemide

Absence of a pharmacokinetic interaction between enalapril and frusemide

Single doses of enalapril maleate 10 mg and frusemide 80 mg do not significantly affect the pharmacokinetics of each other when taken concomitantly. Their concomitant use may be associated with more adverse effects than with the individual entities.

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Veröffentlicht in:British journal of clinical pharmacology 1987-01, Vol.23 (1), p.84-87
Hauptverfasser: Hecken, AM, Verbesselt, R, Buntinx, A, Cirillo, VJ, Schepper, PJ
Format: Artikel
Sprache:eng
Schlagworte:
Administration, Oral
Adult
Antihypertensive agents
Biological and medical sciences
Cardiovascular system
Drug Interactions
Enalapril - metabolism
Furosemide - metabolism
Humans
Kinetics
Male
Medical sciences
Pharmacology. Drug treatments
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Zusammenfassung:Single doses of enalapril maleate 10 mg and frusemide 80 mg do not significantly affect the pharmacokinetics of each other when taken concomitantly. Their concomitant use may be associated with more adverse effects than with the individual entities.
ISSN:0306-5251
1365-2125
DOI:10.1111/j.1365-2125.1987.tb03013.x