The effect of membrane polarization on the time course of the end-plate current in frog sartorius muscle

1. Intracellular recordings of the end-plate current at different membrane potentials were made, using a voltage-clamp technique. 2. When the membrane potential is varied between about +40 and -120 mV, the half-decline time of the end-plate current increases from about 0·6 msec to about 1·6 msec....

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Veröffentlicht in:The Journal of physiology 1969-10, Vol.204 (2), p.493-502
1. Verfasser: Kordas, M
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description 1. Intracellular recordings of the end-plate current at different membrane potentials were made, using a voltage-clamp technique. 2. When the membrane potential is varied between about +40 and -120 mV, the half-decline time of the end-plate current increases from about 0·6 msec to about 1·6 msec. 3. It is suggested that the stability of receptor—mediator complex is affected by the membrane potential.
doi_str_mv 10.1113/jphysiol.1969.sp008926
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Intracellular recordings of the end-plate current at different membrane potentials were made, using a voltage-clamp technique. 2. When the membrane potential is varied between about +40 and -120 mV, the half-decline time of the end-plate current increases from about 0·6 msec to about 1·6 msec. 3. 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Intracellular recordings of the end-plate current at different membrane potentials were made, using a voltage-clamp technique. 2. When the membrane potential is varied between about +40 and -120 mV, the half-decline time of the end-plate current increases from about 0·6 msec to about 1·6 msec. 3. 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subjects Animals
Anura
Electrophysiology
Glycerol - pharmacology
In Vitro Techniques
Membrane Potentials
Neuromuscular Junction - physiology
Potassium - metabolism
Sensory Receptor Cells - physiology
Sodium - metabolism
Time Factors
title The effect of membrane polarization on the time course of the end-plate current in frog sartorius muscle
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