Rietveld Refinement on X-Ray Diffraction Patterns of Bioapatite in Human Fetal Bones

Rietveld Refinement on X-Ray Diffraction Patterns of Bioapatite in Human Fetal Bones

Bioapatite, the main constituent of mineralized tissue in mammalian bones, is a calcium-phosphate-based mineral that is similar in structure and composition to hydroxyapatite. In this work, the crystallographic structure of bioapatite in human fetuses was investigated by synchrotron radiation x-ray...

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Veröffentlicht in:Biophysical journal 2003-03, Vol.84 (3), p.2021-2029
Hauptverfasser: Meneghini, Carlo, Dalconi, Maria Chiara, Nuzzo, Stefania, Mobilio, Settimio, Wenk, Rudy H.
Format: Artikel
Sprache:eng
Schlagworte:
Aging - physiology
Algorithms
Anisotropy
Bones
Crystallography - methods
Durapatite - chemistry
Durapatite - metabolism
Fetuses
Gestational Age
Humans
Lumbar Vertebrae - chemistry
Lumbar Vertebrae - embryology
Minerals
Particle Size
Radiology
Spectroscopy, Imaging, Other Techniques
X-Ray Diffraction - methods
X-rays
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Zusammenfassung:Bioapatite, the main constituent of mineralized tissue in mammalian bones, is a calcium-phosphate-based mineral that is similar in structure and composition to hydroxyapatite. In this work, the crystallographic structure of bioapatite in human fetuses was investigated by synchrotron radiation x-ray diffraction (XRD) and microdiffraction ( μ-XRD) techniques. Rietveld refinement analyses of XRD and μ-XRD data allow for quantitative probing of the structural modifications of bioapatite as functions of the mineralization process and gestational age.
ISSN:0006-3495
1542-0086
DOI:10.1016/S0006-3495(03)75010-3