Chronic renal failure associated with topical application of paraphenylenediamine

Paraphenylenediamine ("para"), a derivative of paranitroaniline, is widely used as a hair dye. It has several toxic effects, of which asthma and dermatitis are common. About 4% of apparently normal subjects are sensitive to it, and 1% are acutely sensitive. The authors report two cases of...

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Veröffentlicht in:	BMJ 1987-01, Vol.294 (6565), p.155-155
Hauptverfasser:	Brown, J H, McGeown, M G, Conway, B, Hill, C M
Format:	Artikel
Sprache:	eng
Schlagworte:	Chronic kidney failure Edema Female Glomerulonephritis Hair dyeing Hair Dyes - adverse effects Hair Preparations - adverse effects Henna Humans Kidney Failure, Chronic - chemically induced Lesions Middle Aged Necrosis Phenylenediamines - administration & dosage Phenylenediamines - adverse effects Short Reports Topical application Toxicity Vasculitis
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Beschreibung
Zusammenfassung:	Paraphenylenediamine ("para"), a derivative of paranitroaniline, is widely used as a hair dye. It has several toxic effects, of which asthma and dermatitis are common. About 4% of apparently normal subjects are sensitive to it, and 1% are acutely sensitive. The authors report two cases of vasculitis and crescentic glomerulonephritis after prolonged topical application.
ISSN:	0267-0623 0959-8138 1468-5833
DOI:	10.1136/bmj.294.6565.155