INTERACTION OF ASPARTATE AMINOTRANSFERASE WITH AMINO ACIDS

INTERACTION OF ASPARTATE AMINOTRANSFERASE WITH AMINO ACIDS

1. The capacity of various amino acids to convert the pyridoxal form of aspartate aminotransferase into the pyridoxamine form has been investigated. 2. Glutamate has the highest converting capacity; aspartate, alpha-aminopimelate, alpha-aminoadipate and other amino acids follow. 3. The converting ca...

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Veröffentlicht in:Biochemical Journal 1965-06, Vol.95 (3), p.657-660
Hauptverfasser: SCOTTO, P, SCARDI, V
Format: Artikel
Sprache:eng
Schlagworte:
Adipates
Aldehydes
Amines
Amino Acids
Aspartate Aminotransferases
Aspartic Acid
Chemical Phenomena
Chemistry
Glutamates
Glutamic Acid
Old Medline
Pimelic Acids
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Zusammenfassung:1. The capacity of various amino acids to convert the pyridoxal form of aspartate aminotransferase into the pyridoxamine form has been investigated. 2. Glutamate has the highest converting capacity; aspartate, alpha-aminopimelate, alpha-aminoadipate and other amino acids follow. 3. The converting capacity of the various amino acids assayed is connected with their structural features. 4. A possible role of amino acids as secondary substrates of aspartate aminotransferase is suggested.
ISSN:0264-6021
0006-2936
1470-8728
DOI:10.1042/bj0950657