Isolation and characterization of a photorepair-deficient mutant in Drosophila melanogaster

A mutation abolishing photorepair has been localized to map position 56.8 centimorgans on the second chromosome of Drosophila melanogaster. Strains homozygous for the phr allele are totally devoid of photorepair and partially deficient in excision repair. Both defects map to the chromosomal region b...

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Veröffentlicht in:	Genetics (Austin) 1987-06, Vol.116 (2), p.233-239
Hauptverfasser:	Boyd, J.B, Harris, P.V
Format:	Artikel
Sprache:	eng
Schlagworte:	ACTIVIDAD SOLAR ACTIVITE SOLAIRE Animals Biological and medical sciences Chromosome Mapping Classical genetics, quantitative genetics, hybrids Crosses, Genetic DNA Repair DROSOPHILA Drosophila melanogaster Drosophila melanogaster - genetics Drosophila melanogaster - radiation effects Drosophilidae Female Fundamental and applied biological sciences. Psychology Genetics of eukaryotes. Biological and molecular evolution Invertebrata Investigations LIGHT LUMIERE LUZ Male MUTANT MUTANTES MUTANTS Mutation Recombination, Genetic REPAIRING REPARACION REPARATION SOLAR ACTIVITY Ultraviolet Rays
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Zusammenfassung:	A mutation abolishing photorepair has been localized to map position 56.8 centimorgans on the second chromosome of Drosophila melanogaster. Strains homozygous for the phr allele are totally devoid of photorepair and partially deficient in excision repair. Both defects map to the chromosomal region between pr and c. Since a homozygous phr stock exhibits reduced photoreactivation, the corresponding wild-type allele plays a significant role in UV resistance.
ISSN:	0016-6731 1943-2631 1943-2631
DOI:	10.1093/genetics/116.2.233