THE HOMOZYGOSITY TEST AFTER A CHANGE IN POPULATION SIZE

The homozygosity of a population will be influenced by any recent change in the population size. The "homozygosity test" of the neutral mutation hypothesis might also be influenced by a population change. A computer simulation method is described that establishes the significance levels of...

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Veröffentlicht in:Genetics (Austin) 1986-04, Vol.112 (4), p.899-907
1. Verfasser: Watterson, G. A
Format: Artikel
Sprache:eng
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Zusammenfassung:The homozygosity of a population will be influenced by any recent change in the population size. The "homozygosity test" of the neutral mutation hypothesis might also be influenced by a population change. A computer simulation method is described that establishes the significance levels of observed homozygosities after a change in population size. Some numerical examples are given.
ISSN:0016-6731
1943-2631
1943-2631
DOI:10.1093/genetics/112.4.899