Drug-induced Creutzfeldt-Jakob like syndrome

Drug-induced Creutzfeldt-Jakob like syndrome

A patient with progressive neurological deterioration characterized by cognitive impairment, myoclonus, Parkinson's syndrome, an abnormal electroencephalogram and fasciculations was considered for brain biopsy for suspected Creutzfeldt-Jakob disease. Complete clinical recovery followed disconti...

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Veröffentlicht in:Journal of psychiatry & neuroscience 1992-09, Vol.17 (3), p.103-105
1. Verfasser: Finelli, P F
Format: Artikel
Sprache:eng
Schlagworte:
Creutzfeldt-Jakob Syndrome - chemically induced
Creutzfeldt-Jakob Syndrome - diagnosis
Dementia - chemically induced
Dementia - diagnosis
Depressive Disorder - drug therapy
Electroencephalography - drug effects
Humans
Lithium - adverse effects
Lithium - therapeutic use
Male
Middle Aged
Neuropsychological Tests
Nortriptyline - adverse effects
Nortriptyline - therapeutic use
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Zusammenfassung:A patient with progressive neurological deterioration characterized by cognitive impairment, myoclonus, Parkinson's syndrome, an abnormal electroencephalogram and fasciculations was considered for brain biopsy for suspected Creutzfeldt-Jakob disease. Complete clinical recovery followed discontinuation of lithium and nortriptyline. Awareness of this unusual drug-induced Creutzfeldt-Jakob like syndrome can avoid costly, invasive and unnecessary investigative procedures.
ISSN:1180-4882
1488-2434