Activation of immobilized acetyl-Coenzyme A carboxylase

Partially purified acetyl-CoA carboxylase was covalently bound to a Sepharose 4B matrix. Although aggregation was thus prevented, the enzymic activity was stimulated by citrate and isocitrate.

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Bibliographische Detailangaben
Veröffentlicht in:	Biochemical journal 1978-01, Vol.169 (1), p.255-256
Hauptverfasser:	Landman, A D, Lampert, J
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetyl-CoA Carboxylase - metabolism Citrates - pharmacology Enzyme Activation - drug effects Enzymes, Immobilized - metabolism Ligases - metabolism Macromolecular Substances Sepharose
Online-Zugang:	Volltext
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Beschreibung
Zusammenfassung:	Partially purified acetyl-CoA carboxylase was covalently bound to a Sepharose 4B matrix. Although aggregation was thus prevented, the enzymic activity was stimulated by citrate and isocitrate.
ISSN:	0264-6021 1470-8728
DOI:	10.1042/bj1690255