Relative changes in the function of muscle ribosomes and mitochondria during the early phase of steroid-induced catabolism

1. Five glucocorticoids, when administered daily to rats for 5-7 days at a dosage of 5mg/kg, were in the following order of effectiveness with respect to their ability to decrease the weight gain of whole animals and the vastus lateralis, vastus medialis and gluteus medius muscles: corticosterone

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Bibliographische Detailangaben
Veröffentlicht in:	Biochemical journal 1972-05, Vol.127 (5), p.881-892
Hauptverfasser:	Bullock, G R, Carter, E E, Elliott, P, Peters, R F, Simpson, P, White, A M
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acids - metabolism Animals Betamethasone - pharmacology Body Weight - drug effects Carbon Isotopes Corticosterone - pharmacology Dexamethasone - pharmacology Dose-Response Relationship, Drug Glucocorticoids - pharmacology Leucine - metabolism Male Mitochondria, Muscle - drug effects Muscles - cytology Muscles - drug effects Muscles - metabolism Oxidation-Reduction Prednisolone - pharmacology Rats Ribosomes - drug effects Triamcinolone - pharmacology Triamcinolone Acetonide - pharmacology Tritium
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Beschreibung
Zusammenfassung:	1. Five glucocorticoids, when administered daily to rats for 5-7 days at a dosage of 5mg/kg, were in the following order of effectiveness with respect to their ability to decrease the weight gain of whole animals and the vastus lateralis, vastus medialis and gluteus medius muscles: corticosterone
ISSN:	0264-6021 0306-3283 1470-8728
DOI:	10.1042/bj1270881