Unravelling the ties that bind: The intersection of obesity, osteoarthritis, and inflammatory pathways with emphasis on glucagon‐like peptide‐1 agonists

Summary This narrative review article explores the complex interplay between obesity, osteoarthritis, and their associated inflammatory cascades, offering a deeper understanding of the underlying of mechanisms of inflammation and potential therapeutic interventions targeting both diseases. Through e...

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Veröffentlicht in:Clinical obesity 2025-02, Vol.15 (1), p.e12700-n/a
Hauptverfasser: Jamal, Naadir, Hollabaugh, William, Scott, Leon, Takkouche, Sahar
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Sprache:eng
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Zusammenfassung:Summary This narrative review article explores the complex interplay between obesity, osteoarthritis, and their associated inflammatory cascades, offering a deeper understanding of the underlying of mechanisms of inflammation and potential therapeutic interventions targeting both diseases. Through examination of the shared inflammatory pathway of obesity and osteoarthritis, our objective is to directly elucidate the relationship between these two conditions, highlighting the promising role of glucagon‐like peptide‐1 agonists in modulating inflammation and its therapeutic implications for patients with obesity and osteoarthritis. Unravelling the ties that bind: The intersection of obesity, osteoarthritis, and inflammatory pathways with emphasis on glucagon‐like peptide‐1 agonists.
ISSN:1758-8103
1758-8111
DOI:10.1111/cob.12700