The effect of uncouplers on catecholamine incorporation by vesicles of chromaffin granules

It is shown that uncouplers inhibit the incorporation of catecholamines by vesicles of chromaffin granules in parallel with their stimulatory effect on the membrane-bound adenosine triphosphatase.

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Bibliographische Detailangaben
Veröffentlicht in:	Biochemical journal 1975-04, Vol.148 (1), p.153-155
Hauptverfasser:	Bashford, C L, Casey, R P, Radda, G K, Ritchie, G A
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenosine Triphosphatases - analysis Adenosine Triphosphate - metabolism Adrenal Medulla - drug effects Adrenal Medulla - metabolism Adrenal Medulla - ultrastructure Animals Catecholamines - metabolism Cattle Cytoplasmic Granules - drug effects In Vitro Techniques Magnesium - metabolism Uncoupling Agents - pharmacology
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Beschreibung
Zusammenfassung:	It is shown that uncouplers inhibit the incorporation of catecholamines by vesicles of chromaffin granules in parallel with their stimulatory effect on the membrane-bound adenosine triphosphatase.
ISSN:	0264-6021 1470-8728
DOI:	10.1042/bj1480153