Obstructive Sleep Apnea and Chronic Rhinosinusitis: Understanding the Impact of OSA on CRS Disease Burden

Objective Assess the impact of obstructive sleep apnea (OSA) on chronic rhinosinusitis (CRS) severeity. Study Design Retrospective database review. Setting TriNetX US database. Methods TriNetX US Collaborative Network database was queried for cohorts of patients with OSA, CRS, and CRS with comorbid OSA (CRS‐OSA). Data included demographics, CRS severity was assessed via rates of endoscopic sinus surgery (ESS), antibiotic, and oral steroid use. Propensity score matching was performed to account for differences in demographics and clinical variables. Results The query identified 1,818,879 patients with CRS, 481144 with OSA, and 93,153 CRS‐OSA patients. OSA‐CRS patients had higher rates of hypertension, diabetes mellitus, obesity, and asthma than either CRS or OSA populations (P