The Association Between Diabetic Nephropathy and Triglyceride/Glucose Index and Triglyceride/High-Density Lipoprotein Cholesterol Ratio in Patients with Type 2 Diabetes Mellitus

The Association Between Diabetic Nephropathy and Triglyceride/Glucose Index and Triglyceride/High-Density Lipoprotein Cholesterol Ratio in Patients with Type 2 Diabetes Mellitus

In this study, we aimed to investigate the relationship between diabetic nephropathy (DN) and triglyceride/glucose (TyG) index and triglyceride/high-density lipoprotein cholesterol ratio (Tg/HDL-C) as surrogate markers of insulin resistance. Medical records of 15,378 individuals between February 201...

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Veröffentlicht in:Journal of clinical medicine 2024-11, Vol.13 (22), p.6954
Hauptverfasser: Tam, Abbas Ali, Altay, Feride Pınar, Demir, Pervin, Ozdemir, Didem, Topaloglu, Oya, Ersoy, Reyhan, Cakır, Bekir
Format: Artikel
Sprache:eng
Schlagworte:
Blood sugar monitoring
Cholesterol, HDL
Complications and side effects
Creatinine
Diabetes
Diabetic nephropathies
Diabetic nephropathy
Females
Gender
Glucose
Health aspects
Insulin
Kidney diseases
Measurement
Patients
Regression analysis
Risk factors
Triglycerides
Type 2 diabetes
Variables
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Zusammenfassung:In this study, we aimed to investigate the relationship between diabetic nephropathy (DN) and triglyceride/glucose (TyG) index and triglyceride/high-density lipoprotein cholesterol ratio (Tg/HDL-C) as surrogate markers of insulin resistance. Medical records of 15,378 individuals between February 2019 and May 2024 were examined. Serum glucose, Tg, HDL-C, HbA1c, estimated glomerular filtration rate (eGFR), and urine albumin/creatinine ratio (UACR) were evaluated and the TyG index and TG/HDL-C ratios were calculated for each individual. DN was defined as a UACR ≥ 30 mg/g and/or eGFR
ISSN:2077-0383
2077-0383
DOI:10.3390/jcm13226954