Diagnosis, treatment, and long‐term outcomes of pediatric pemphigus: a retrospective study at tertiary medical centers

Background Pediatric pemphigus is a rare bullous disease that represents a diagnostic and therapeutic challenge; evidence on patients' response to various treatments and long‐term surveillance data are lacking. We aimed to investigate pediatric pemphigus patients' characteristics, diagnos...

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Veröffentlicht in:	International journal of dermatology 2024-12, Vol.63 (12), p.1755-1760
Hauptverfasser:	Renert‐Yuval, Yael, Baum, Sharon, Greenberger, Shoshana, Cohen‐Barak, Eran, Oren‐Shabtai, Meital, Ben‐Amitai, Dan, Friedland, Rivka
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adrenal Cortex Hormones - administration & dosage Adrenal Cortex Hormones - therapeutic use Bullous diseases Child Child, Preschool Corticoids Corticosteroids Delayed Diagnosis - statistics & numerical data Diagnosis Diagnostic systems Disease control Female Follow-Up Studies Glucocorticoids - administration & dosage Glucocorticoids - therapeutic use Health care facilities Health services Humans Immunofluorescence Immunomodulation Immunomodulators Israel - epidemiology Male Medical treatment Original Patients pediatric dermatology Pediatrics Pemphigus Pemphigus - diagnosis Pemphigus - drug therapy Pemphigus - therapy pemphigus foliaceus pemphigus vulgaris Remission Retrospective Studies Rituximab Rituximab - administration & dosage Rituximab - therapeutic use Tapering Tertiary Care Centers - statistics & numerical data Time Factors Treatment Outcome
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Zusammenfassung:	Background Pediatric pemphigus is a rare bullous disease that represents a diagnostic and therapeutic challenge; evidence on patients' response to various treatments and long‐term surveillance data are lacking. We aimed to investigate pediatric pemphigus patients' characteristics, diagnosis, therapeutics, response, and long‐term follow‐up. Methods This is a retrospective study of all pemphigus patients aged
ISSN:	0011-9059 1365-4632 1365-4632
DOI:	10.1111/ijd.17251