Effect of an 18-Month Meditation Training on Telomeres in Older Adults: A Secondary Analysis of the Age-Well Randomized Controlled Trial

Effect of an 18-Month Meditation Training on Telomeres in Older Adults: A Secondary Analysis of the Age-Well Randomized Controlled Trial

Shorter telomeres are associated with increased risk of cognitive decline and age-related diseases. Developing interventions to promote healthy aging by preserving telomere integrity is of paramount importance. Here, we investigated the effect of an 18-month meditation intervention on telomere lengt...

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Veröffentlicht in:Biological psychiatry global open science 2025-01, Vol.5 (1), p.100398, Article 100398
Hauptverfasser: Kaliman, Perla, Álvarez-López, María Jesús, Lehodey, Asrar, Fernández, Daniel, Chocat, Anne, Schlosser, Marco, de La Sayette, Vincent, Vivien, Denis, Marchant, Natalie L., Chételat, Gael, Lutz, Antoine, Poisnel, Géraldine, André, Claire, Lugo, Sebastian Baez, Batchelor, Martine, Beaugonin, Axel, Champetier, Pierre, Chauveau, Léa, Collette, Fabienne, De Florès, Robin, Delarue, Marion, Fauvel, Séverine, Felisatti, Francesca, Devouge, Eglantine Ferrand, Frison, Eric, Gonneaud, Julie, Tran, Thien Huong, Klimecki, Olga, Kuhn, Elizabeth, Landeau, Brigitte, Lefranc, Valérie, Marchant, Natalie, Mezenge, Florence, Ourry, Valentin, Palix, Cassandre, Quillard, Anne, Rauchs, Géraldine, Salmon, Eric, Schimmer, Corinne, Touron, Edelweiss, Turpin, Anne-Laure, Vuilleumier, Patrik
Format: Artikel
Sprache:eng
Schlagworte:
Aging
Archival Report
Human health and pathology
Life Sciences
Meditation
PBMC
Personality
Prevention
Randomized controlled trial
Telomere
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Zusammenfassung:Shorter telomeres are associated with increased risk of cognitive decline and age-related diseases. Developing interventions to promote healthy aging by preserving telomere integrity is of paramount importance. Here, we investigated the effect of an 18-month meditation intervention on telomere length (TL) measures in older people without cognitive impairment. A total of 137 adults age ≥65 years were randomized to one of the 3 groups (meditation training, non-native language training, or passive control). We evaluated the 50th and 20th percentile TL and the percentage of critically short telomeres (
ISSN:2667-1743
2667-1743
DOI:10.1016/j.bpsgos.2024.100398