The Effectiveness of Heat-Killed Pediococcus acidilactici K15 in Preventing Respiratory Tract Infections in Preterm Infants: A Pilot Double-Blind, Randomized, Placebo-Controlled Study

The Effectiveness of Heat-Killed Pediococcus acidilactici K15 in Preventing Respiratory Tract Infections in Preterm Infants: A Pilot Double-Blind, Randomized, Placebo-Controlled Study

Preterm infants discharged from the neonatal intensive care unit (NICU) have a risk of severe viral respiratory tract infections (RTIs). Researchers have recently reported the potential use of postbiotics to decrease RTIs in young children. However, the safety and efficacy of postbiotics for prevent...

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Veröffentlicht in:Nutrients 2024-10, Vol.16 (21), p.3635
Hauptverfasser: Takeshita, Kenichi, Hishiki, Haruka, Takei, Haruka, Ikari, Naho, Tanaka, Saori, Iijima, Yuta, Ogata, Hitoshi, Fujishiro, Kensuke, Tominaga, Takahiro, Konno, Yuki, Iwase, Yukiko, Nakano, Taiji, Endo, Mamiko, Ishiwada, Naruhiko, Osone, Yoshiteru, Kawaguchi, Tomohiro, Horiba, Taro, Takemura, Ryo, Hamada, Hiromichi, Shimojo, Naoki
Format: Artikel
Sprache:eng
Schlagworte:
Analysis
B cells
Bacteria
Care and treatment
Clinical trials
Disease
Double-Blind Method
Esters
Feces
Female
Food
Food industry
Gestational age
Hospitals
Hot Temperature
Humans
Immune system
Immunoglobulins
Infant, Newborn
Infant, Premature
Infants (Premature)
Infection
Infection control
Infections
Intensive Care Units, Neonatal
Male
Medical research
Medicine, Experimental
Microbiota
Neonatal intensive care
Newborn babies
Pediococcus acidilactici
Pilot Projects
Premature babies
Premature birth
Prevention
Probiotics
Probiotics - administration & dosage
Respiratory tract diseases
Respiratory Tract Infections - microbiology
Respiratory Tract Infections - prevention & control
RNA
Siblings
Viral infections
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Zusammenfassung:Preterm infants discharged from the neonatal intensive care unit (NICU) have a risk of severe viral respiratory tract infections (RTIs). Researchers have recently reported the potential use of postbiotics to decrease RTIs in young children. However, the safety and efficacy of postbiotics for preventing RTIs in preterm infants is not yet established. We conducted a pilot double-blind, randomized, placebo-controlled study of the heat-killed lactic acid bacterium K15 in 41 preterm infants born at
ISSN:2072-6643
2072-6643
DOI:10.3390/nu16213635