Effects of insulin in vitro on lipogenesis and fatty acid uptake in white adipose tissue of Zucker rats aged 10 days

Adipose-tissue lipogenesis and fatty acid uptake in vitro were higher in obese than in lean Zucker rats aged 10 days. On average, insulin stimulated each of these two metabolic pathways to the same extent in both genotypes. However, in fa/fa pups, we observed that insulin stimulation decreased when...

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Veröffentlicht in:	Biochemical journal 1984-03, Vol.218 (2), p.653-655
Hauptverfasser:	de Waziers, I, Planche, E
Format:	Artikel
Sprache:	eng
Schlagworte:	Adipose Tissue - drug effects Adipose Tissue - metabolism Animals Fatty Acids - metabolism In Vitro Techniques Insulin - pharmacology Lipids - biosynthesis Obesity - metabolism Rats Rats, Zucker
Online-Zugang:	Volltext
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Zusammenfassung:	Adipose-tissue lipogenesis and fatty acid uptake in vitro were higher in obese than in lean Zucker rats aged 10 days. On average, insulin stimulated each of these two metabolic pathways to the same extent in both genotypes. However, in fa/fa pups, we observed that insulin stimulation decreased when adipose-tissue weight increased.
ISSN:	0264-6021 1470-8728
DOI:	10.1042/bj2180653