Utility of time in tight range (TITR) in evaluating metabolic control in pediatric and adult patients with type 1 diabetes in treatment with advanced hybrid closed-loop systems

Purpose To analyze the time in tight range (TITR), and its relationship with other glucometric parameters in patients with type 1 diabetes (T1D) treated with advanced hybrid closed-loop (AHCL) systems. Methods A prospective observational study was conducted on pediatric and adult patients with T1D u...

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Veröffentlicht in:	Endocrine 2024-11, Vol.86 (2), p.539-545
Hauptverfasser:	Bahillo-Curieses, Pilar, Fernández Velasco, Pablo, Pérez-López, Paloma, Vidueira Martínez, Ana María, Nieto de la Marca, María de la O, Díaz-Soto, Gonzalo
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Blood Glucose - analysis Blood Glucose Self-Monitoring - methods Child Diabetes Diabetes Mellitus, Type 1 - blood Diabetes Mellitus, Type 1 - drug therapy Endocrinology Female Glycated Hemoglobin - analysis Glycemic Control - methods Humanities and Social Sciences Humans Hypoglycemic Agents - administration & dosage Hypoglycemic Agents - therapeutic use Insulin - administration & dosage Insulin - therapeutic use Insulin Infusion Systems Internal Medicine Male Medicine Medicine & Public Health Middle Aged multidisciplinary Original Original Article Prospective Studies Science Time Factors Treatment Outcome Young Adult
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Zusammenfassung:	Purpose To analyze the time in tight range (TITR), and its relationship with other glucometric parameters in patients with type 1 diabetes (T1D) treated with advanced hybrid closed-loop (AHCL) systems. Methods A prospective observational study was conducted on pediatric and adult patients with T1D undergoing treatment with AHCL systems for at least 3 months. Clinical variables and glucometric parameters before and after AHCL initiation were collected. Results A total of 117 patients were evaluated. Comparison of metabolic control after AHCL initiation showed significant improvements in HbA1c (6.9 ± 0.9 vs. 6.6 ± 0.5%, p
ISSN:	1559-0100 1355-008X 1559-0100
DOI:	10.1007/s12020-024-03881-6