Acquired Low Factor XIII Activity Is Associated with an Increased Need for Blood Transfusions in Patients with Gastrointestinal Bleedings

Acquired Low Factor XIII Activity Is Associated with an Increased Need for Blood Transfusions in Patients with Gastrointestinal Bleedings

Background Factor XIII plays a key role within the coagulation cascade. Objective We aimed to investigate the relevance of factor XIII activity on the outcome of patients with gastrointestinal bleedings. Methods In this retrospective, single-center study patients with gastrointestinal bleeding and m...

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Veröffentlicht in:Digestive diseases and sciences 2024-10, Vol.69 (10), p.3894-3900
Hauptverfasser: Traninger, Anna, Blesl, Andreas, Borenich, Andrea, Fürst, Stefan, Wagner, Thomas, Raggam, Reinhard Bernd, Berghold, Andrea, Högenauer, Christoph
Format: Artikel
Sprache:eng
Schlagworte:
Biochemistry
Blood
Blood transfusions
Digestive system
Gastroenterology
Hemorrhage
Hepatology
Medicine
Medicine & Public Health
Oncology
Original
Original Article
Transplant Surgery
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Zusammenfassung:Background Factor XIII plays a key role within the coagulation cascade. Objective We aimed to investigate the relevance of factor XIII activity on the outcome of patients with gastrointestinal bleedings. Methods In this retrospective, single-center study patients with gastrointestinal bleeding and measurement of factor XIII activity were included. The primary endpoint was the number of red blood cell transfusions in patients with reduced factor XIII activity (
ISSN:0163-2116
1573-2568
1573-2568
DOI:10.1007/s10620-024-08651-y