Association between the triglyceride-glucose index and spine fracture: A cross-sectional study of American adults
It is yet unknown how spine fracture in adults relate to the triglyceride-glucose (TyG) index. This study investigated the link between TyG index and spine fracture in the adult population of the United States by analyzing information derived from the National Health and Nutrition Examination Survey...
Gespeichert in:
Veröffentlicht in: | Medicine (Baltimore) 2024-10, Vol.103 (41), p.e40119 |
---|---|
Hauptverfasser: | , , |
Format: | Artikel |
Sprache: | eng |
Schlagworte: | |
Online-Zugang: | Volltext |
Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
container_end_page | |
---|---|
container_issue | 41 |
container_start_page | e40119 |
container_title | Medicine (Baltimore) |
container_volume | 103 |
creator | Geng, Maosen Lv, Cheng Zhang, Ke |
description | It is yet unknown how spine fracture in adults relate to the triglyceride-glucose (TyG) index. This study investigated the link between TyG index and spine fracture in the adult population of the United States by analyzing information derived from the National Health and Nutrition Examination Survey. Ultimately, this study comprised 10,187 participants was drawn from the National Health and Nutrition Examination Survey (2005-2010, 2013-2014, and 2017-2020). The Participants were divided into quartiles by the TyG index, and correlations between the TyG index and spine fracture were found using subgroup statistical analysis, restricted cubic spline curves, receiver operating characteristic analysis, and weighted multiple regression. Eventually, we carried 10,187 individuals, of whom 211 (2.1%) had an incident spine fracture. The results of the adjusted multivariate logistic regression analysis shows that the TyG index increased the morbidity of spine fracture (odds ratios: 1.63, 95% confidence intervals: 1.15-2.30, P = .01) and the outcome of the stratified and sensitivity analyses remained stable and indicative of a nonlinear relationship. The findings of our study indicate that an elevated TyG index is associated with an increased susceptibility to spine fracture and demonstrates a moderate level of predictive capability. |
doi_str_mv | 10.1097/MD.0000000000040119 |
format | Article |
fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11479443</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>3121283265</sourcerecordid><originalsourceid>FETCH-LOGICAL-c286t-bade0e81110b5f8172b8e55d9ef91e698e1611b7a3b3578e023e123c85cbad443</originalsourceid><addsrcrecordid>eNpdkclOxDAMhiMEYn8CJJQjl0LcNG3KBY3YJRAXOEdp6g5BnWRIUmDenrIvvtiS_X-2_BOyA2wfWF0dXJ_ss58oGEC9RNZB8DITdVks_6rXyEaMD4wBr_JilazxuiiFZGKdPE5i9MbqZL2jDaZnREfTPdIU7LRfGAy2xWzaD8ZHpNa1-EK1a2mcW4e0C9qkIeAhnVATfIxZRPOG0j2NaWgX1Hd0MhshRjuq26FPcYusdLqPuP2ZN8nd2ent8UV2dXN-eTy5ykwuy5Q1ukWGEgBYIzoJVd5IFKKtsasBy1oilABNpXnDRSWR5Rwh50YKM0qLgm-Sow_ufGhm2Bp0KehezYOd6bBQXlv1t-PsvZr6JwVQVPUIGAl7n4TgHweMSc1sNNj32qEfouKQQy55XopxlH-Mvn8hYPe9B5h6c0tdn6j_bo2q3d8nfmu-7OGvfjySjA</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>3121283265</pqid></control><display><type>article</type><title>Association between the triglyceride-glucose index and spine fracture: A cross-sectional study of American adults</title><source>IngentaConnect</source><source>Wolters Kluwer Open Health</source><source>MEDLINE</source><source>PubMed Central</source><source>Directory of Open Access Journals</source><source>Alma/SFX Local Collection</source><source>EZB Electronic Journals Library</source><creator>Geng, Maosen ; Lv, Cheng ; Zhang, Ke</creator><creatorcontrib>Geng, Maosen ; Lv, Cheng ; Zhang, Ke</creatorcontrib><description>It is yet unknown how spine fracture in adults relate to the triglyceride-glucose (TyG) index. This study investigated the link between TyG index and spine fracture in the adult population of the United States by analyzing information derived from the National Health and Nutrition Examination Survey. Ultimately, this study comprised 10,187 participants was drawn from the National Health and Nutrition Examination Survey (2005-2010, 2013-2014, and 2017-2020). The Participants were divided into quartiles by the TyG index, and correlations between the TyG index and spine fracture were found using subgroup statistical analysis, restricted cubic spline curves, receiver operating characteristic analysis, and weighted multiple regression. Eventually, we carried 10,187 individuals, of whom 211 (2.1%) had an incident spine fracture. The results of the adjusted multivariate logistic regression analysis shows that the TyG index increased the morbidity of spine fracture (odds ratios: 1.63, 95% confidence intervals: 1.15-2.30, P = .01) and the outcome of the stratified and sensitivity analyses remained stable and indicative of a nonlinear relationship. The findings of our study indicate that an elevated TyG index is associated with an increased susceptibility to spine fracture and demonstrates a moderate level of predictive capability.</description><identifier>ISSN: 1536-5964</identifier><identifier>ISSN: 0025-7974</identifier><identifier>EISSN: 1536-5964</identifier><identifier>DOI: 10.1097/MD.0000000000040119</identifier><identifier>PMID: 39465805</identifier><language>eng</language><publisher>United States: Lippincott Williams & Wilkins</publisher><subject>Adult ; Aged ; Blood Glucose - analysis ; Cross-Sectional Studies ; Female ; Humans ; Male ; Middle Aged ; Nutrition Surveys ; Observational Study ; Risk Factors ; Spinal Fractures - blood ; Spinal Fractures - epidemiology ; Triglycerides - blood ; United States - epidemiology</subject><ispartof>Medicine (Baltimore), 2024-10, Vol.103 (41), p.e40119</ispartof><rights>Copyright © 2024 the Author(s). Published by Wolters Kluwer Health, Inc.</rights><rights>Copyright © 2024 the Author(s). Published by Wolters Kluwer Health, Inc. 2024</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c286t-bade0e81110b5f8172b8e55d9ef91e698e1611b7a3b3578e023e123c85cbad443</cites><orcidid>0000-0002-7129-171 ; 0000-0002-7129-171X</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC11479443/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC11479443/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,723,776,780,860,881,27901,27902,53766,53768</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/39465805$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Geng, Maosen</creatorcontrib><creatorcontrib>Lv, Cheng</creatorcontrib><creatorcontrib>Zhang, Ke</creatorcontrib><title>Association between the triglyceride-glucose index and spine fracture: A cross-sectional study of American adults</title><title>Medicine (Baltimore)</title><addtitle>Medicine (Baltimore)</addtitle><description>It is yet unknown how spine fracture in adults relate to the triglyceride-glucose (TyG) index. This study investigated the link between TyG index and spine fracture in the adult population of the United States by analyzing information derived from the National Health and Nutrition Examination Survey. Ultimately, this study comprised 10,187 participants was drawn from the National Health and Nutrition Examination Survey (2005-2010, 2013-2014, and 2017-2020). The Participants were divided into quartiles by the TyG index, and correlations between the TyG index and spine fracture were found using subgroup statistical analysis, restricted cubic spline curves, receiver operating characteristic analysis, and weighted multiple regression. Eventually, we carried 10,187 individuals, of whom 211 (2.1%) had an incident spine fracture. The results of the adjusted multivariate logistic regression analysis shows that the TyG index increased the morbidity of spine fracture (odds ratios: 1.63, 95% confidence intervals: 1.15-2.30, P = .01) and the outcome of the stratified and sensitivity analyses remained stable and indicative of a nonlinear relationship. The findings of our study indicate that an elevated TyG index is associated with an increased susceptibility to spine fracture and demonstrates a moderate level of predictive capability.</description><subject>Adult</subject><subject>Aged</subject><subject>Blood Glucose - analysis</subject><subject>Cross-Sectional Studies</subject><subject>Female</subject><subject>Humans</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Nutrition Surveys</subject><subject>Observational Study</subject><subject>Risk Factors</subject><subject>Spinal Fractures - blood</subject><subject>Spinal Fractures - epidemiology</subject><subject>Triglycerides - blood</subject><subject>United States - epidemiology</subject><issn>1536-5964</issn><issn>0025-7974</issn><issn>1536-5964</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2024</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpdkclOxDAMhiMEYn8CJJQjl0LcNG3KBY3YJRAXOEdp6g5BnWRIUmDenrIvvtiS_X-2_BOyA2wfWF0dXJ_ss58oGEC9RNZB8DITdVks_6rXyEaMD4wBr_JilazxuiiFZGKdPE5i9MbqZL2jDaZnREfTPdIU7LRfGAy2xWzaD8ZHpNa1-EK1a2mcW4e0C9qkIeAhnVATfIxZRPOG0j2NaWgX1Hd0MhshRjuq26FPcYusdLqPuP2ZN8nd2ent8UV2dXN-eTy5ykwuy5Q1ukWGEgBYIzoJVd5IFKKtsasBy1oilABNpXnDRSWR5Rwh50YKM0qLgm-Sow_ufGhm2Bp0KehezYOd6bBQXlv1t-PsvZr6JwVQVPUIGAl7n4TgHweMSc1sNNj32qEfouKQQy55XopxlH-Mvn8hYPe9B5h6c0tdn6j_bo2q3d8nfmu-7OGvfjySjA</recordid><startdate>20241011</startdate><enddate>20241011</enddate><creator>Geng, Maosen</creator><creator>Lv, Cheng</creator><creator>Zhang, Ke</creator><general>Lippincott Williams & Wilkins</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>5PM</scope><orcidid>https://orcid.org/0000-0002-7129-171</orcidid><orcidid>https://orcid.org/0000-0002-7129-171X</orcidid></search><sort><creationdate>20241011</creationdate><title>Association between the triglyceride-glucose index and spine fracture: A cross-sectional study of American adults</title><author>Geng, Maosen ; Lv, Cheng ; Zhang, Ke</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c286t-bade0e81110b5f8172b8e55d9ef91e698e1611b7a3b3578e023e123c85cbad443</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2024</creationdate><topic>Adult</topic><topic>Aged</topic><topic>Blood Glucose - analysis</topic><topic>Cross-Sectional Studies</topic><topic>Female</topic><topic>Humans</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Nutrition Surveys</topic><topic>Observational Study</topic><topic>Risk Factors</topic><topic>Spinal Fractures - blood</topic><topic>Spinal Fractures - epidemiology</topic><topic>Triglycerides - blood</topic><topic>United States - epidemiology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Geng, Maosen</creatorcontrib><creatorcontrib>Lv, Cheng</creatorcontrib><creatorcontrib>Zhang, Ke</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Medicine (Baltimore)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Geng, Maosen</au><au>Lv, Cheng</au><au>Zhang, Ke</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Association between the triglyceride-glucose index and spine fracture: A cross-sectional study of American adults</atitle><jtitle>Medicine (Baltimore)</jtitle><addtitle>Medicine (Baltimore)</addtitle><date>2024-10-11</date><risdate>2024</risdate><volume>103</volume><issue>41</issue><spage>e40119</spage><pages>e40119-</pages><issn>1536-5964</issn><issn>0025-7974</issn><eissn>1536-5964</eissn><abstract>It is yet unknown how spine fracture in adults relate to the triglyceride-glucose (TyG) index. This study investigated the link between TyG index and spine fracture in the adult population of the United States by analyzing information derived from the National Health and Nutrition Examination Survey. Ultimately, this study comprised 10,187 participants was drawn from the National Health and Nutrition Examination Survey (2005-2010, 2013-2014, and 2017-2020). The Participants were divided into quartiles by the TyG index, and correlations between the TyG index and spine fracture were found using subgroup statistical analysis, restricted cubic spline curves, receiver operating characteristic analysis, and weighted multiple regression. Eventually, we carried 10,187 individuals, of whom 211 (2.1%) had an incident spine fracture. The results of the adjusted multivariate logistic regression analysis shows that the TyG index increased the morbidity of spine fracture (odds ratios: 1.63, 95% confidence intervals: 1.15-2.30, P = .01) and the outcome of the stratified and sensitivity analyses remained stable and indicative of a nonlinear relationship. The findings of our study indicate that an elevated TyG index is associated with an increased susceptibility to spine fracture and demonstrates a moderate level of predictive capability.</abstract><cop>United States</cop><pub>Lippincott Williams & Wilkins</pub><pmid>39465805</pmid><doi>10.1097/MD.0000000000040119</doi><orcidid>https://orcid.org/0000-0002-7129-171</orcidid><orcidid>https://orcid.org/0000-0002-7129-171X</orcidid><oa>free_for_read</oa></addata></record> |
fulltext | fulltext |
identifier | ISSN: 1536-5964 |
ispartof | Medicine (Baltimore), 2024-10, Vol.103 (41), p.e40119 |
issn | 1536-5964 0025-7974 1536-5964 |
language | eng |
recordid | cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11479443 |
source | IngentaConnect; Wolters Kluwer Open Health; MEDLINE; PubMed Central; Directory of Open Access Journals; Alma/SFX Local Collection; EZB Electronic Journals Library |
subjects | Adult Aged Blood Glucose - analysis Cross-Sectional Studies Female Humans Male Middle Aged Nutrition Surveys Observational Study Risk Factors Spinal Fractures - blood Spinal Fractures - epidemiology Triglycerides - blood United States - epidemiology |
title | Association between the triglyceride-glucose index and spine fracture: A cross-sectional study of American adults |
url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-14T19%3A15%3A37IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Association%20between%20the%20triglyceride-glucose%20index%20and%20spine%20fracture:%20A%20cross-sectional%20study%20of%20American%20adults&rft.jtitle=Medicine%20(Baltimore)&rft.au=Geng,%20Maosen&rft.date=2024-10-11&rft.volume=103&rft.issue=41&rft.spage=e40119&rft.pages=e40119-&rft.issn=1536-5964&rft.eissn=1536-5964&rft_id=info:doi/10.1097/MD.0000000000040119&rft_dat=%3Cproquest_pubme%3E3121283265%3C/proquest_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=3121283265&rft_id=info:pmid/39465805&rfr_iscdi=true |