Association between the triglyceride-glucose index and spine fracture: A cross-sectional study of American adults

It is yet unknown how spine fracture in adults relate to the triglyceride-glucose (TyG) index. This study investigated the link between TyG index and spine fracture in the adult population of the United States by analyzing information derived from the National Health and Nutrition Examination Survey...

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Veröffentlicht in:Medicine (Baltimore) 2024-10, Vol.103 (41), p.e40119
Hauptverfasser: Geng, Maosen, Lv, Cheng, Zhang, Ke
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Lv, Cheng
Zhang, Ke
description It is yet unknown how spine fracture in adults relate to the triglyceride-glucose (TyG) index. This study investigated the link between TyG index and spine fracture in the adult population of the United States by analyzing information derived from the National Health and Nutrition Examination Survey. Ultimately, this study comprised 10,187 participants was drawn from the National Health and Nutrition Examination Survey (2005-2010, 2013-2014, and 2017-2020). The Participants were divided into quartiles by the TyG index, and correlations between the TyG index and spine fracture were found using subgroup statistical analysis, restricted cubic spline curves, receiver operating characteristic analysis, and weighted multiple regression. Eventually, we carried 10,187 individuals, of whom 211 (2.1%) had an incident spine fracture. The results of the adjusted multivariate logistic regression analysis shows that the TyG index increased the morbidity of spine fracture (odds ratios: 1.63, 95% confidence intervals: 1.15-2.30, P = .01) and the outcome of the stratified and sensitivity analyses remained stable and indicative of a nonlinear relationship. The findings of our study indicate that an elevated TyG index is associated with an increased susceptibility to spine fracture and demonstrates a moderate level of predictive capability.
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This study investigated the link between TyG index and spine fracture in the adult population of the United States by analyzing information derived from the National Health and Nutrition Examination Survey. Ultimately, this study comprised 10,187 participants was drawn from the National Health and Nutrition Examination Survey (2005-2010, 2013-2014, and 2017-2020). The Participants were divided into quartiles by the TyG index, and correlations between the TyG index and spine fracture were found using subgroup statistical analysis, restricted cubic spline curves, receiver operating characteristic analysis, and weighted multiple regression. Eventually, we carried 10,187 individuals, of whom 211 (2.1%) had an incident spine fracture. The results of the adjusted multivariate logistic regression analysis shows that the TyG index increased the morbidity of spine fracture (odds ratios: 1.63, 95% confidence intervals: 1.15-2.30, P = .01) and the outcome of the stratified and sensitivity analyses remained stable and indicative of a nonlinear relationship. 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The results of the adjusted multivariate logistic regression analysis shows that the TyG index increased the morbidity of spine fracture (odds ratios: 1.63, 95% confidence intervals: 1.15-2.30, P = .01) and the outcome of the stratified and sensitivity analyses remained stable and indicative of a nonlinear relationship. 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subjects Adult
Aged
Blood Glucose - analysis
Cross-Sectional Studies
Female
Humans
Male
Middle Aged
Nutrition Surveys
Observational Study
Risk Factors
Spinal Fractures - blood
Spinal Fractures - epidemiology
Triglycerides - blood
United States - epidemiology
title Association between the triglyceride-glucose index and spine fracture: A cross-sectional study of American adults
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