Severe Optic Neuropathy Induced by Very Prolonged Tedizolid as Suppressive Therapy: Description of a Case Report and Implication for Better Assessment

Abstract The long-term tolerability of linezolid is low because of mitochondrial toxicity, whereas tedizolid may represent a better option for suppressive therapy. We report a first presumed case of tedizolid-associated optic neuropathy after a very prolonged (18-month) intake and believe that scree...

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Veröffentlicht in:Open Forum Infectious Diseases 2024-09, Vol.11 (9), p.ofae517
Hauptverfasser: Coustilleres, F, Thillard, E M, Khanna, R K, Olivereau, S, Ouaissi, M, Pansu, N, Le Lez, M L
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Sprache:eng
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Zusammenfassung:Abstract The long-term tolerability of linezolid is low because of mitochondrial toxicity, whereas tedizolid may represent a better option for suppressive therapy. We report a first presumed case of tedizolid-associated optic neuropathy after a very prolonged (18-month) intake and believe that screening for optic neuropathy should be considered for patients undergoing tedizolid suppression.
ISSN:2328-8957
2328-8957
DOI:10.1093/ofid/ofae517