Functional dependence following intensive care unit-treated sepsis: three-year follow-up results from the prospective Mid-German Sepsis Cohort (MSC)

Surviving sepsis can lead to chronic physical, psychological and cognitive impairments, which affect millions of patients worldwide, including survivors after COVID-19 viral sepsis. We aimed to characterize the magnitude and trajectory of functional dependence and new impairments post-sepsis. We con...

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Veröffentlicht in:The Lancet regional health. Europe 2024-11, Vol.46, p.101066, Article 101066
Hauptverfasser: Fleischmann-Struzek, Carolin, Born, Sebastian, Kesselmeier, Miriam, Ely, E. Wesley, Töpfer, Kristin, Romeike, Heike, Bauer, Michael, Bercker, Sven, Bodechtel, Ulf, Fiedler, Sandra, Groesdonk, Heinrich V., Petros, Sirak, Platzer, Stefanie, Rüddel, Hendrik, Schreiber, Torsten, Reinhart, Konrad, Scherag, André
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Sprache:eng
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Zusammenfassung:Surviving sepsis can lead to chronic physical, psychological and cognitive impairments, which affect millions of patients worldwide, including survivors after COVID-19 viral sepsis. We aimed to characterize the magnitude and trajectory of functional dependence and new impairments post-sepsis. We conducted a prospective cohort study including sepsis survivors who had been discharged from five German intensive care units (ICUs), until 36 months post-discharge. Primary outcome was functional dependence, defined as ≥1 impaired activity of daily living (ADL; 10-item ADL score
ISSN:2666-7762
2666-7762
DOI:10.1016/j.lanepe.2024.101066