Correlation of urine cytology with ABO(H) antigenicity in transitional cell carcinoma of the bladder

Cell surface ABO(H) antigenicity of superficial bladder tumours was assessed by the indirect immunoperoxidase test in 49 patients. Good correlation was obtained between surface antigenicity of tumours and the results of urine cytology. Malignant cells were detected cytologically in 22(56%) of cases...

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Veröffentlicht in:	Journal of clinical pathology 1988-05, Vol.41 (5), p.538-539
Hauptverfasser:	Das, G, Glashan, R W
Format:	Artikel
Sprache:	eng
Schlagworte:	ABO Blood-Group System - immunology Aged Aged, 80 and over Antigens, Surface - analysis Biological and medical sciences Carcinoma, Transitional Cell - blood Carcinoma, Transitional Cell - immunology Carcinoma, Transitional Cell - pathology Female Humans Male Medical sciences Middle Aged Nephrology. Urinary tract diseases Tumors of the urinary system Urinary Bladder Neoplasms - blood Urinary Bladder Neoplasms - immunology Urinary Bladder Neoplasms - pathology Urinary tract. Prostate gland Urine - cytology
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Zusammenfassung:	Cell surface ABO(H) antigenicity of superficial bladder tumours was assessed by the indirect immunoperoxidase test in 49 patients. Good correlation was obtained between surface antigenicity of tumours and the results of urine cytology. Malignant cells were detected cytologically in 22(56%) of cases with ABO(H) antigen negative tumours which are known to behave more aggressively than ABO(H) antigen positive ones. In contrast, malignant cells were found in the urine cytology of only one (10%) of patients with ABO(H) antigen positive tumours.
ISSN:	0021-9746 1472-4146
DOI:	10.1136/jcp.41.5.538