Influence of Menstrual Cycle and Oral Contraceptive Phases on Bone (re)modelling Markers in Response to Interval Running

To explore how sex hormone fluctuations may affect bone metabolism, this study aimed to examine P1NP and β-CTX-1 concentrations across the menstrual and oral contraceptive (OC) cycle phases in response to running. 17β-oestradiol, progesterone, P1NP and β-CTX-1 were analysed pre- and post-exercise in...

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Veröffentlicht in:Calcified tissue international 2024-10, Vol.115 (4), p.382-392
Hauptverfasser: Guisado-Cuadrado, Isabel, Romero-Parra, Nuria, Elliott-Sale, Kirsty J., Sale, Craig, Díaz, Ángel E., Peinado, Ana B.
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Sprache:eng
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Zusammenfassung:To explore how sex hormone fluctuations may affect bone metabolism, this study aimed to examine P1NP and β-CTX-1 concentrations across the menstrual and oral contraceptive (OC) cycle phases in response to running. 17β-oestradiol, progesterone, P1NP and β-CTX-1 were analysed pre- and post-exercise in eight eumenorrheic females in the early-follicular, late-follicular, and mid-luteal phases, while 8 OC users were evaluated during the withdrawal and active pill-taking phases. The running protocol consisted of 8 × 3min treadmill runs at 85% of maximal aerobic speed. 17β-oestradiol concentrations (pg·ml −1 ) were lower in early-follicular (47.22 ± 39.75) compared to late-follicular (304.95 ± 235.85; p  =  
ISSN:1432-0827
0171-967X
1432-0827
DOI:10.1007/s00223-024-01259-4