Phosphorylation of the tight-junction protein ZO-1 in two strains of Madin-Darby canine kidney cells which differ in transepithelial resistance
A comparison was made of the phosphate content of the tight-junction-specific protein ZO-1 in two strains of Madin-Darby canine kidney cells which differ in transepithelial resistance, a parameter reflective of tight-junctional permeability. Analysis revealed that the ZO-1 from the low-resistance st...
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Veröffentlicht in: | Biochemical journal 1989-10, Vol.263 (2), p.597-599 |
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description | A comparison was made of the phosphate content of the tight-junction-specific protein ZO-1 in two strains of Madin-Darby canine kidney cells which differ in transepithelial resistance, a parameter reflective of tight-junctional permeability. Analysis revealed that the ZO-1 from the low-resistance strain contained approximately twice as much phosphate as that from the high-resistance strain. |
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Analysis revealed that the ZO-1 from the low-resistance strain contained approximately twice as much phosphate as that from the high-resistance strain.</description><identifier>ISSN: 0264-6021</identifier><identifier>EISSN: 1470-8728</identifier><identifier>DOI: 10.1042/bj2630597</identifier><identifier>PMID: 2597123</identifier><language>eng</language><publisher>England</publisher><subject>Animals ; Cell Line ; Cell Membrane Permeability ; Dogs ; Electric Conductivity ; Epithelium - physiology ; Intercellular Junctions - physiology ; Kidney - physiology ; Kinetics ; MDCK cells ; Membrane Proteins - metabolism ; Phosphates - metabolism ; Phosphoproteins - metabolism ; Phosphorylation ; proteins ; Zonula Occludens-1 Protein</subject><ispartof>Biochemical journal, 1989-10, Vol.263 (2), p.597-599</ispartof><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c3827-89d389192228a4bc9ca509b65f69b4d83df3b7d5f2498da1447c9dc1dffee8773</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC1133468/pdf/$$EPDF$$P50$$Gpubmedcentral$$H</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC1133468/$$EHTML$$P50$$Gpubmedcentral$$H</linktohtml><link.rule.ids>230,314,727,780,784,885,27924,27925,53791,53793</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/2597123$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Stevenson, B R</creatorcontrib><creatorcontrib>Anderson, J M</creatorcontrib><creatorcontrib>Braun, I D</creatorcontrib><creatorcontrib>Mooseker, M S</creatorcontrib><title>Phosphorylation of the tight-junction protein ZO-1 in two strains of Madin-Darby canine kidney cells which differ in transepithelial resistance</title><title>Biochemical journal</title><addtitle>Biochem J</addtitle><description>A comparison was made of the phosphate content of the tight-junction-specific protein ZO-1 in two strains of Madin-Darby canine kidney cells which differ in transepithelial resistance, a parameter reflective of tight-junctional permeability. 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Analysis revealed that the ZO-1 from the low-resistance strain contained approximately twice as much phosphate as that from the high-resistance strain.</abstract><cop>England</cop><pmid>2597123</pmid><doi>10.1042/bj2630597</doi><tpages>3</tpages><oa>free_for_read</oa></addata></record> |
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source | MEDLINE; EZB-FREE-00999 freely available EZB journals; PubMed Central; Alma/SFX Local Collection |
subjects | Animals Cell Line Cell Membrane Permeability Dogs Electric Conductivity Epithelium - physiology Intercellular Junctions - physiology Kidney - physiology Kinetics MDCK cells Membrane Proteins - metabolism Phosphates - metabolism Phosphoproteins - metabolism Phosphorylation proteins Zonula Occludens-1 Protein |
title | Phosphorylation of the tight-junction protein ZO-1 in two strains of Madin-Darby canine kidney cells which differ in transepithelial resistance |
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