Enhanced oxidative stability of deuterated squalene: the impact of labelling extent on chemical resilience

Enhanced oxidative stability of deuterated squalene: the impact of labelling extent on chemical resilience

The extent to which deuteration affects the oxidative stability of squalene, a nutrient and a commonly-used ingredient in cosmetics and vaccine adjuvants, has been quantified as a function of the extent of labelling. The formation of comedogenic peroxides was inhibited by levels of overall deuterati...

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Veröffentlicht in:RSC advances 2024-08, Vol.14 (36), p.26002-26006
Hauptverfasser: Möller, Johanna, Recsei, Carl, Russell, Robert, Darwish, Tamim
Format: Artikel
Sprache:eng
Schlagworte:
Adjuvants
Chemistry
Cosmetics
Deuteration
Labeling
Peroxides
Stability
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Zusammenfassung:The extent to which deuteration affects the oxidative stability of squalene, a nutrient and a commonly-used ingredient in cosmetics and vaccine adjuvants, has been quantified as a function of the extent of labelling. The formation of comedogenic peroxides was inhibited by levels of overall deuteration as low as 19%.
ISSN:2046-2069
2046-2069
DOI:10.1039/d4ra05543h