Central Obesity is Associated with Increased Left Ventricular Maximal Wall Thickness and Intrathoracic Adipose Tissue Measured with Cardiac Magnetic Resonance

Introduction Central obesity (CO), characterized by an increased waist circumference increases the risk of cardiovascular disease (CVD) and morbidity, yet the underlying mechanisms are not fully understood. CO is often associated with general obesity, hypertension, and abnormal glucose tolerance, co...

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Veröffentlicht in:	High Blood Pressure & Cardiovascular Prevention 2024-07, Vol.31 (4), p.389-399
Hauptverfasser:	Marttila, Jarkko, Sipola, Petri, Juutilainen, Auni, Sillanmäki, Saara, Hedman, Marja, Kuusisto, Johanna
Format:	Artikel
Sprache:	eng
Schlagworte:	Adipose Tissue - diagnostic imaging Adipose Tissue - physiopathology Adiposity Adult Blood pressure Body fat Body Mass Index Cardiology Cardiovascular disease Case-Control Studies Cross-Sectional Studies Diabetes Glucose Health risks Heart Humans Hypertension Hypertrophy, Left Ventricular - diagnostic imaging Hypertrophy, Left Ventricular - etiology Hypertrophy, Left Ventricular - physiopathology Magnetic Resonance Imaging Magnetic Resonance Imaging, Cine Male Medicine Medicine & Public Health Metabolic syndrome Middle Aged Mortality Obesity Obesity, Abdominal - complications Obesity, Abdominal - diagnostic imaging Obesity, Abdominal - physiopathology Original Original Article Pharmacotherapy Predictive Value of Tests Software Ventricular Function, Left Ventricular Remodeling Waist Circumference
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Zusammenfassung:	Introduction Central obesity (CO), characterized by an increased waist circumference increases the risk of cardiovascular disease (CVD) and morbidity, yet the underlying mechanisms are not fully understood. CO is often associated with general obesity, hypertension, and abnormal glucose tolerance, confounding the independent contribution of CO to CVD. Aim We investigated the relationship of CO (without associated disorders) with left ventricular (LV) characteristics and intrathoracic adipose tissue (IAT) by cardiac magnetic resonance. Methods LV characteristics, epicardial (EAT), and mediastinal adipose tissue (MAT) were measured from 29 normoglycemic, normotensive males with CO but without general obesity (waist circumference >100 cm, body mass index (BMI)
ISSN:	1179-1985 1120-9879 1179-1985
DOI:	10.1007/s40292-024-00659-9