Shining a light on cerebral autoregulation: Are we anywhere near the truth?

The near-infrared spectroscopy (NIRS)-derived cerebral oximetry index (COx) has become popularized for non-invasive neuromonitoring of cerebrovascular function in post-cardiac arrest patients with hypoxic-ischemic brain injury (HIBI). We provide commentary on the physiologic underpinnings and assump...

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Veröffentlicht in:	Journal of cerebral blood flow and metabolism 2024-06, Vol.44 (6), p.1057-1060
Hauptverfasser:	Bird, Jordan D, MacLeod, David B, Griesdale, Donald E, Sekhon, Mypinder S, Hoiland, Ryan L
Format:	Artikel
Sprache:	eng
Schlagworte:	Brain - blood supply Brain - metabolism Brain - physiopathology Cerebrovascular Circulation - physiology Commentaries Heart Arrest - physiopathology Homeostasis - physiology Humans Hypoxia-Ischemia, Brain - physiopathology Oximetry - methods Spectroscopy, Near-Infrared - methods
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Beschreibung
Zusammenfassung:	The near-infrared spectroscopy (NIRS)-derived cerebral oximetry index (COx) has become popularized for non-invasive neuromonitoring of cerebrovascular function in post-cardiac arrest patients with hypoxic-ischemic brain injury (HIBI). We provide commentary on the physiologic underpinnings and assumptions of NIRS and the COx, potential confounds in the context of HIBI, and the implications for the assessment of cerebral autoregulation.
ISSN:	0271-678X 1559-7016 1559-7016
DOI:	10.1177/0271678X241245488