Missed Opportunities for Preexposure Prophylaxis Initiation in Hospitalized Persons With Opioid Use Disorder and Infectious Diseases

Abstract Hospitalizations are increasing among persons who use opioids, secondary to overdose and infections. Our study identified acute hospitalization as a reachable moment for engaging people who use drugs in increased screening and education about human immunodeficiency virus risk and prevention (preexposure prophylaxis). In patients with opioid use disorder admitted to the hospital for an infection, less than half had heard of preexposure prophylaxis (PrEP) and none were taking PrEP. The majority of patients believed they had no or low risk of HIV infection.