Genome sequences of the 15 bluetongue virus vaccine strains incorporated in the South African live-attenuated vaccine

Bluetongue disease in endemic areas is predominantly controlled through vaccination with live-attenuated vaccines. Sequencing of the original master seed viruses used in the production of Onderstepoort Biological Products vaccine was conducted. Nucleotide identities of 82.97%-100% were obtained for...

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Veröffentlicht in:Microbiology resource announcements 2024-06, Vol.13 (6), p.e0022324
Hauptverfasser: Mlingo, Tendai A M, Beeton-Kempen, Natasha, Nthangeni, M Bethuel, Theron, Jacques, Mokoena, Nobalanda B
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Sprache:eng
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Zusammenfassung:Bluetongue disease in endemic areas is predominantly controlled through vaccination with live-attenuated vaccines. Sequencing of the original master seed viruses used in the production of Onderstepoort Biological Products vaccine was conducted. Nucleotide identities of 82.97%-100% were obtained for all sequences when compared to South African reference strains.
ISSN:2576-098X
2576-098X
DOI:10.1128/mra.00223-24