Temporal Trends in the Outcomes of Percutaneous Coronary Intervention With Zotarolimus Eluting Stents Versus Everolimus Eluting Stents: A Meta‐Analysis of Randomized Controlled Trials

ABSTRACT Introduction Long‐term follow‐up results of various trials comparing Zotarolimus eluting stents (ZES) with Everolimus eluting stents (EES) have been published recently. Additionally, over the last decade, there have been new trials comparing the ZES with various commercially available EES....

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Veröffentlicht in:	Clinical cardiology (Mahwah, N.J.) N.J.), 2024-06, Vol.47 (6), p.e24306-n/a
Hauptverfasser:	Basit, Jawad, Ahmed, Mushood, Shafiq, Aimen, Zaheer, Zaofashan, Nashwan, Abdulqadir J., Ahmed, Aleena, Hamza, Mohammad, Naseer, Usman, Ali, Shafaqat, Gupta, Neelesh, Sattar, Yasar, Kawsara, Akram, Daggubati, Ramesh, Alraies, M. Chadi
Format:	Artikel
Sprache:	eng
Schlagworte:	Angioplasty Bias Cardiovascular Agents - administration & dosage Clinical outcomes Clinical trials Coronary Artery Disease - surgery Coronary Artery Disease - therapy Drug-Eluting Stents Everolimus - administration & dosage Everolimus - pharmacology Everolimus‐eluting stents (EES) Humans Intervention major adverse cardiovascular events (MACE) Meta-analysis Patients Percutaneous Coronary Intervention - instrumentation Percutaneous Coronary Intervention - methods Polymers Prosthesis Design randomized controlled trials Randomized Controlled Trials as Topic Review Risk Factors Sirolimus - administration & dosage Sirolimus - analogs & derivatives Sirolimus - pharmacology Smooth muscle Stents Systematic review target vessel myocardial infarction (TVMI) Thrombosis Time Factors Treatment Outcome Zotarolimus‐eluting stents (ZES)
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Zusammenfassung:	ABSTRACT Introduction Long‐term follow‐up results of various trials comparing Zotarolimus eluting stents (ZES) with Everolimus eluting stents (EES) have been published recently. Additionally, over the last decade, there have been new trials comparing the ZES with various commercially available EES. We aim to conduct an updated meta‐analysis in light of new evidence from randomized controlled trials (RCTs) to provide comprehensive evidence regarding the temporal trends in the clinical outcomes. Methods A comprehensive literature search was conducted across PubMed, Cochrane, and Embase. RCTs comparing ZES with EES for short (
ISSN:	0160-9289 1932-8737 1932-8737
DOI:	10.1002/clc.24306