VLDL and LDL Subfractions Enhance the Risk Stratification of Individuals Who Underwent Epstein–Barr Virus‐Based Screening for Nasopharyngeal Carcinoma: A Multicenter Cohort Study (Adv. Sci. 22/2024)

Nasopharyngeal Carcinoma Comprehensive lipoprotein profiling and metabolite analysis reveal significant metabolic reprogramming within nasopharyngeal carcinoma (NPC) patients. Small, dense VLDL‐5 particles and large, buoyant LDL‐1 particles hold promise as novel biomarkers for nasopharyngeal carcinoma. NMR‐based risk score (NRS) is constructed based on signature metabolites, VLDL‐5 and LDL‐1 subfractions, which demonstrates excellent capability of personalized risk prediction, and provides a brand‐new clinical perspective for early screening of NPC. More details can be found in article number 2308765 by Zhen Cai, Laiyu Liu, Jian Guan, and co‐workers.