Prior polymyalgia rheumatica is associated with sonographic vasculitic changes in newly diagnosed patients with giant cell arteritis

Abstract Objectives To investigate the hypothesis that a history of PMR is associated with a more severe and damaging disease course in newly diagnosed GCA patients. Methods This was a retrospective analysis of GCA patients diagnosed between December 2006 and May 2021. We compared vascular ultrasoun...

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Veröffentlicht in:Rheumatology (Oxford, England) England), 2024-05, Vol.63 (6), p.1523-1527
Hauptverfasser: Hemmig, Andrea K, Aschwanden, Markus, Berger, Christoph T, Kyburz, Diego, Mensch, Noemi, Staub, Daniel, Stegert, Mihaela, Imfeld, Stephan, Daikeler, Thomas
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Sprache:eng
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Zusammenfassung:Abstract Objectives To investigate the hypothesis that a history of PMR is associated with a more severe and damaging disease course in newly diagnosed GCA patients. Methods This was a retrospective analysis of GCA patients diagnosed between December 2006 and May 2021. We compared vascular ultrasound findings (presence of vasculitis and vascular stenosis) in GCA patients with and without prior PMR. Results Forty-nine of 311 GCA patients (15.8%) had prior PMR in a median of 30.6 (IQR 7.1–67.3) months before GCA diagnosis. Patients with prior PMR more often had large vessel vasculitis (LVV) (51.0% vs 25.0%, P 
ISSN:1462-0324
1462-0332
1462-0332
DOI:10.1093/rheumatology/kead450