Are miR‐26a and miR‐26b microRNAs potent prognostic markers of gestational diabetes?

Background Gestational diabetes mellitus is a common public health problem, accompanied by complications for the mother and fetus. So, introducing new biomarkers to identify early diabetes is essential. As serum miRNAs are potentially appropriate markers, we investigated miR‐26a and miR‐26b expression levels in pregnant women with and without gestational diabetes. Method Demographic and clinical characteristics of 40 gestational diabetic patients and 40 healthy controls were assessed. The expression level of miR‐26a and miR‐26b microRNAs was measured by real‐time PCR. Statistical analysis was done with GraphPad Prism software (version 8.4.3). Result The findings of this study showed that the expression level of miR‐26a and miR‐26b increased in women with gestational diabetes compared with healthy pregnant women, but the increase in expression was only significant for miR‐26a (p